Literature DB >> 2006923

c-myc mRNA in cytoskeletal-bound polysomes in fibroblasts.

J E Hesketh1, G P Campbell, P F Whitelaw.   

Abstract

3T3 fibroblasts were treated sequentially with 25 mM-KCl/0.05% Nonidet P40, 130 mM-KCl/0.05% Nonidet P40 and finally with 1% Nonidet P40/1% deoxycholate in order to release free, cytoskeletal-bound and membrane-bound polysomes respectively. The membrane-bound fraction was enriched in the mRNA for the membrane protein beta 2-microglobulin, whereas the cytoskeletal-bound polysomes were enriched in c-myc mRNA. Actin mRNA was present in both free and cytoskeletal-bound polysomes. The results suggest that cytoskeletal-bound polysomes are involved in the translation of specific mRNA species.

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Year:  1991        PMID： 2006923      PMCID： PMC1150182          DOI： 10.1042/bj2740607

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  17 in total

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Authors:  R C Bird; B H Sells
Journal:  Biochim Biophys Acta       Date:  1986-12-18

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Authors:  J E Hesketh; G P Campbell; P J Reeds
Journal:  Biosci Rep       Date:  1986-09       Impact factor: 3.840

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Journal:  Exp Cell Res       Date:  1989-04       Impact factor: 3.905

5.  Attachment of mRNA to the cytoskeletal framework and translational control of gene expression in rat L6 muscle cells.

Authors:  J Bag; S Pramanik
Journal:  Biochem Cell Biol       Date:  1987-06       Impact factor: 3.626

Review 6.  Functional studies of polysome-membrane interactions in vitro.

Authors:  T K Shires; H C Pitot
Journal:  Adv Enzyme Regul       Date:  1973

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Authors:  J E Hesketh; I F Pryme
Journal:  FEBS Lett       Date:  1988-04-11       Impact factor: 4.124

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Authors:  M D Pondel; M L King
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

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Authors:  N K Banskota; R Taub; K Zellner; P Olsen; G L King
Journal:  Diabetes       Date:  1989-01       Impact factor: 9.461

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Authors:  R H Singer; G L Langevin; J B Lawrence
Journal:  J Cell Biol       Date:  1989-06       Impact factor: 10.539
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  18 in total

1.  Annexin II is associated with mRNAs which may constitute a distinct subpopulation.

Authors:  A Vedeler; H Hollås
Journal:  Biochem J       Date:  2000-06-15       Impact factor: 3.857

2.  An AU-rich stem-loop structure is a critical feature of the perinuclear localization signal of c-myc mRNA.

Authors:  Hervé Chabanon; Ian Mickleburgh; Brian Burtle; Christopher Pedder; John Hesketh
Journal:  Biochem J       Date:  2005-12-15       Impact factor: 3.857

3.  Elongation factor 1alpha binds to the region of the metallothionein-1 mRNA implicated in perinuclear localization--importance of an internal stem-loop.

Authors:  Ian Mickleburgh; Hervé Chabanon; David Nury; Kunbo Fan; Brian Burtle; Zofia Chrzanowska-Lightowlers; John Hesketh
Journal:  RNA       Date:  2006-05-24       Impact factor: 4.942

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Authors:  J E Hesketh; I F Pryme
Journal:  Biochem J       Date:  1991-07-01       Impact factor: 3.857

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Authors:  Stephane R Gross; Terri Goss Kinzy
Journal:  Mol Cell Biol       Date:  2006-12-18       Impact factor: 4.272

6.  The mRNAs for cyclin A, c-myc and ribosomal proteins L4 and S6 are associated with cytoskeletal-bound polysomes in HepG2 cells.

Authors:  R Hovland; G Campbell; I Pryme; J Hesketh
Journal:  Biochem J       Date:  1995-08-15       Impact factor: 3.857

7.  Tracing MYC Expression for Small Molecule Discovery.

Authors:  Jutta Steinberger; Francis Robert; Maxime Hallé; David E Williams; Regina Cencic; Neha Sawhney; Dylan Pelletier; Philip Williams; Yasuhiro Igarashi; John A Porco; Abimael D Rodriguez; Brigitte Kopp; Brian Bachmann; Raymond J Andersen; Jerry Pelletier
Journal:  Cell Chem Biol       Date:  2019-03-14       Impact factor: 8.116

Review 8.  Translation and the cytoskeleton: a mechanism for targeted protein synthesis.

Authors:  J Hesketh
Journal:  Mol Biol Rep       Date:  1994-05       Impact factor: 2.316

9.  Free, cytoskeletal-bound and membrane-bound polysomes isolated from MPC-11 and Krebs II ascites cells differ in their complement of poly(A) binding proteins.

Authors:  R Moss; I F Pryme; A Vedeler
Journal:  Mol Cell Biochem       Date:  1994-02-23       Impact factor: 3.396

10.  Expression of Escherichia coli homoserine kinase in mouse 3T3 cells.

Authors:  W D Rees; S M Hay; H J Flint
Journal:  Biochem J       Date:  1992-02-01       Impact factor: 3.857
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