Literature DB >> 20065986

Prediction of severe neurogenic bowel dysfunction in persons with spinal cord injury.

C-W Liu1, C-C Huang, C-H Chen, Y-H Yang, T-W Chen, M-H Huang.   

Abstract

STUDY
DESIGN: Cross-sectional study.
OBJECTIVE: To analyze the predictors of severe neurogenic bowel dysfunction (NBD) in persons with spinal cord injury (SCI).
SETTING: The Kaohsiung Medical University Hospital, Taiwan.
METHODS: Two questionnaires-the NBD score and the Beck Depression Inventory second edition-were sent to 232 persons with SCI by mail. The demographic factors and injury-related factors were recorded to evaluate any relationships with severe NBD. The associations between the severity of NBD and psychological condition were also measured.
RESULTS: In all, 39.4% of the respondents suffered from severe NBD. Multiple logistic regression analysis showed that those with a cervical injury (odds ratios (OR)=10.5, 95% confidence interval (CI) 1.6-67.7) or a thoracic injury (OR=7.1, 95% CI 1.2-40.3) had a higher risk of severe NBD than those with a lumbar injury. Persons with American Spinal Injury Association (ASIA) A had a 12.8-fold higher risk of severe NBD than persons with ASIA D (OR=12.8, 95% CI 3.3-50.1). Longer duration of injury (> or =10 years) was another risk factor of severe NBD. Moderate-to-severe depression was associated with reduced bowel function.
CONCLUSIONS: This study showed that high level of cord lesion, completeness of cord injury and longer duration of injury (> or =10 years) could predict the severity of NBD in patients with SCI.

Entities:  

Mesh:

Year:  2010        PMID: 20065986     DOI: 10.1038/sc.2009.181

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


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Review 3.  Bowel Dysfunction in Spinal Cord Injury.

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10.  Enteric Nervous System Remodeling in a Rat Model of Spinal Cord Injury: A Pilot Study.

Authors:  Chloë Lefèvre; Anne Bessard; Philippe Aubert; Charles Joussain; François Giuliano; Delphine Behr-Roussel; Marie-Aimée Perrouin-Verbe; Brigitte Perrouin-Verbe; Charlène Brochard; Michel Neunlist
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