Literature DB >> 20065012

HIV protease inhibitors, indinavir or nelfinavir, augment antimalarial action of artemisinin in vitro.

Lokesh C Mishra1, Amit Bhattacharya, Manish Sharma, Virendra K Bhasin.   

Abstract

Most malaria endemic regions are co-infested with HIV infection. Treatment of one may affect outcome of the other in co-infected individuals. HIV protease inhibitors, indinavir or nelfinavir, are important antiretroviral drugs and artemisinin is central to malaria treatment. We show these protease inhibitors augment the antimalarial activity of artemisinin against P. falciparum in vitro.

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Year:  2010        PMID: 20065012      PMCID: PMC2803526          DOI: 10.4269/ajtmh.2010.09-0427

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  21 in total

1.  In vitro interactions of artemisinin with atovaquone, quinine, and mefloquine against Plasmodium falciparum.

Authors:  S Gupta; M M Thapar; W H Wernsdorfer; A Björkman
Journal:  Antimicrob Agents Chemother       Date:  2002-05       Impact factor: 5.191

2.  Synergy, antagonism, and what the chequerboard puts between them.

Authors:  F C Odds
Journal:  J Antimicrob Chemother       Date:  2003-06-12       Impact factor: 5.790

3.  Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum.

Authors:  Quinton L Fivelman; Ipemida S Adagu; David C Warhurst
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

Review 4.  Newer antiretroviral agents and how to use them.

Authors:  Holly H Kim; Eric S Daar
Journal:  Curr HIV/AIDS Rep       Date:  2009-05       Impact factor: 5.071

5.  Effect of HIV-1 and increasing immunosuppression on malaria parasitaemia and clinical episodes in adults in rural Uganda: a cohort study.

Authors:  J Whitworth; D Morgan; M Quigley; A Smith; B Mayanja; H Eotu; N Omoding; M Okongo; S Malamba; A Ojwiya
Journal:  Lancet       Date:  2000-09-23       Impact factor: 79.321

6.  Human malaria parasites in continuous culture.

Authors:  W Trager; J B Jensen
Journal:  Science       Date:  1976-08-20       Impact factor: 47.728

7.  Artemisinins target the SERCA of Plasmodium falciparum.

Authors:  U Eckstein-Ludwig; R J Webb; I D A Van Goethem; J M East; A G Lee; M Kimura; P M O'Neill; P G Bray; S A Ward; S Krishna
Journal:  Nature       Date:  2003-08-21       Impact factor: 49.962

8.  The effect of artemisinin combined with standard antimalarials against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum in vitro.

Authors:  A N Chawira; D C Warhurst
Journal:  J Trop Med Hyg       Date:  1987-02

9.  Synchronization of Plasmodium falciparum erythrocytic stages in culture.

Authors:  C Lambros; J P Vanderberg
Journal:  J Parasitol       Date:  1979-06       Impact factor: 1.276

10.  Pyrimethamine sensitivity in Plasmodium falciparum: determination in vitro by a modified 48-hour test.

Authors:  P Nguyen-Dinh; D Payne
Journal:  Bull World Health Organ       Date:  1980       Impact factor: 9.408

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  8 in total

1.  HIV-1 protease inhibitors and clinical malaria: a secondary analysis of the AIDS Clinical Trials Group A5208 study.

Authors:  Kimberly A Porter; Stephen R Cole; Joseph J Eron; Yu Zheng; Michael D Hughes; Shahin Lockman; Charles Poole; Tina S Skinner-Adams; Mina Hosseinipour; Doug Shaffer; Ronald D'Amico; Frederick K Sawe; Abraham Siika; Elizabeth Stringer; Judith S Currier; Tsungai Chipato; Robert Salata; James S McCarthy; Steven R Meshnick
Journal:  Antimicrob Agents Chemother       Date:  2011-11-28       Impact factor: 5.191

2.  In vitro activity of antiretroviral drugs against Plasmodium falciparum.

Authors:  Christian Nsanzabana; Philip J Rosenthal
Journal:  Antimicrob Agents Chemother       Date:  2011-08-29       Impact factor: 5.191

3.  Evaluation of Paracheck-Pf(TM) rapid malaria diagnostic test for the diagnosis of malaria among HIV-positive patients in Ibadan, south-western Nigeria.

Authors:  C O Falade; B Adesina-Adewole; H O Dada-Adegbola; I O Ajayi; J O Akinyemi; O G Ademowo; I F Adewole; P Kanki
Journal:  Pathog Glob Health       Date:  2013-03       Impact factor: 2.894

Review 4.  Nelfinavir and other protease inhibitors in cancer: mechanisms involved in anticancer activity.

Authors:  Tomas Koltai
Journal:  F1000Res       Date:  2015-01-12

5.  Evaluation of standard diagnostic rapid test kits for malaria diagnosis among HIV patients in Kano, Nigeria.

Authors:  Henry A Mbah; Feyisayo E Jegede; Surajudeen A Abdulrahman; Tinuade I Oyeyi
Journal:  Afr J Lab Med       Date:  2018-12-05

Review 6.  Multipurpose Drugs Active Against Both Plasmodium spp. and Microorganisms: Potential Application for New Drug Development.

Authors:  Takuro Endo; Hitoshi Takemae; Indu Sharma; Tetsuya Furuya
Journal:  Front Cell Infect Microbiol       Date:  2021-12-24       Impact factor: 5.293

7.  Anemia and Red Blood Cell Abnormalities in HIV-Infected and HIV-Exposed Breastfed Infants: A Secondary Analysis of the Kisumu Breastfeeding Study.

Authors:  Collins Odhiambo; Clement Zeh; Pascale Ondoa; Paul Omolo; Benta Akoth; Humphrey Lwamba; Richard Lando; John Williamson; Juliana Otieno; Rose Masaba; Paul Weidle; Timothy Thomas
Journal:  PLoS One       Date:  2015-11-03       Impact factor: 3.240

Review 8.  Malaria and HIV coinfection in sub-Saharan Africa: prevalence, impact, and treatment strategies.

Authors:  Tebit E Kwenti
Journal:  Res Rep Trop Med       Date:  2018-07-27
  8 in total

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