OBJECTIVE: To examine resting awake EEG in adolescent AN participants before and after refeeding to determine if EEG abnormalities in Anorexia Nervosa (AN) are reversible. METHOD: In 37 adolescent first admission AN patients and 45 healthy controls, EEG was recorded during short duration "eyes open" and "eyes closed" awake resting conditions. Repeat testing occurred in 28 AN participants after refeeding and subsequent weight gain. RESULTS: In "eyes open," underweight AN participants exhibit reduced relative alpha power and increased beta power in frontal brain regions. A significant increase in alpha, and decrease in beta and delta power was observed within participants after refeeding. In "eyes closed", underweight AN participants had elevated theta in parietal-occipital regions which remained after refeeding. DISCUSSION: EEG abnormalities (reduced alpha/increased beta power) in AN normalizes with refeeding, while increased theta power persists in parietal-occipital regions in an eyes closed context.
OBJECTIVE: To examine resting awake EEG in adolescent AN participants before and after refeeding to determine if EEG abnormalities in Anorexia Nervosa (AN) are reversible. METHOD: In 37 adolescent first admission AN patients and 45 healthy controls, EEG was recorded during short duration "eyes open" and "eyes closed" awake resting conditions. Repeat testing occurred in 28 AN participants after refeeding and subsequent weight gain. RESULTS: In "eyes open," underweight AN participants exhibit reduced relative alpha power and increased beta power in frontal brain regions. A significant increase in alpha, and decrease in beta and delta power was observed within participants after refeeding. In "eyes closed", underweight AN participants had elevated theta in parietal-occipital regions which remained after refeeding. DISCUSSION: EEG abnormalities (reduced alpha/increased beta power) in AN normalizes with refeeding, while increased theta power persists in parietal-occipital regions in an eyes closed context.
Authors: John E Leikauf; Kristi R Griffiths; Manish Saggar; David S Hong; Simon Clarke; Daryl Efron; Tracey W Tsang; Daniel F Hermens; Michael R Kohn; Leanne M Williams Journal: Pers Med Psychiatry Date: 2017-03-18
Authors: Christoph Born; Larissa de la Fontaine; Bettina Winter; Norbert Müller; Annette Schaub; Clemens Früstück; Cornelius Schüle; Ulrich Voderholzer; Ulrich Cuntz; Peter Falkai; Eva Meisenzahl Journal: BMC Psychiatry Date: 2015-03-24 Impact factor: 3.630