Literature DB >> 20063

The Environmental fate of three carcinogens: benzo-(alpha)-pyrene, benzidine, and vinyl chloride evaluated in laboratory model ecosystems.

P Y Lu, R L Metcalf, N Plummer, D Mandel.   

Abstract

Radiolabeled benzo-((alpha)-pyrene, benzidine, and vinyl chloride were evaluated in laboratory model ecosystems for environmental fate, degradation pathways, bioconcentration, and food chain accumulation. The comparative effects of microsomal detoxications were evaluated using the inhibitor piperonyl butoxide. The accumulation and bioconcentration of benzo-(alpha)-pyrene and benzidine were closely correlated with their octanol/water partition coefficients and water solubility. Benzo-(alpha)-pyrene as predicted by these parameters was bioaccumulated to substantial levels in several organisms. Vinyl chloride was not accumulated because of its high volatility.

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Year:  1977        PMID： 20063     DOI： 10.1007/BF02097756

Source DB:  PubMed          Journal:  Arch Environ Contam Toxicol        ISSN： 0090-4341            Impact factor:   2.804


  10 in total

1.  Vinyl-chloride-induced liver disease. From idiopathic portal hypertension (Banti's syndrome) to Angiosarcomas.

Authors:  L B Thomas; H Popper; P D Berk; I Selikoff; H Falk
Journal:  N Engl J Med       Date:  1975-01-02       Impact factor: 91.245

2.  Determination of C-14 and H3 in biological samples by Schoeniger combustion and liquid scintillation techniques.

Authors:  R G KELLY; E A PEETS; S GORDON; D A BUYSKE
Journal:  Anal Biochem       Date:  1961-06       Impact factor: 3.365

3.  The hazards to health in the hydrogenation of coal. 4. The control program and the clinical effects.

Authors:  R J SEXTON
Journal:  Arch Environ Health       Date:  1960-09

4.  Chemical carcinogenesis: a long-neglected field blossoms.

Authors:  T H Maugh
Journal:  Science       Date:  1974-03-08       Impact factor: 47.728

Review 5.  Mixed-function oxidase involvement in the biochemistry of insecticide synergists.

Authors:  J E Casida
Journal:  J Agric Food Chem       Date:  1970 Sep-Oct       Impact factor: 5.279

6.  Biochemistry of selective toxicity and biodegradability: comparative O-dealkylation by aquatic organisms.

Authors:  L G Hansen; I P Kapoor; R L Metcalf
Journal:  Comp Gen Pharmacol       Date:  1972-09

7.  Cancer by county: new resource for etiologic clues.

Authors:  R Hoover; T J Mason; F W McKay; J F Fraumeni
Journal:  Science       Date:  1975-09-19       Impact factor: 47.728

8.  Inhalation carcinogenicity of alpha halo ethers. III. Lifetime and limited period inhalation studies with bis(chloromethyl)ether at 0.1 ppm.

Authors:  M Kuschner; S Laskin; R T Drew; V Cappiello; N Nelson
Journal:  Arch Environ Health       Date:  1975-02

Review 9.  Benzidine revisited: a review of the literature and problems associated with the use of benzidine and its congeners.

Authors:  T J Haley
Journal:  Clin Toxicol       Date:  1975       Impact factor: 4.467

10.  Environmental fate and biodegradability of benzene derivatives as studied in a model aquatic ecosystem.

Authors:  P Y Lu; R L Metcalf
Journal:  Environ Health Perspect       Date:  1975-04       Impact factor: 9.031
  10 in total
  8 in total

Review 1.  Biodegradation of high-molecular-weight polycyclic aromatic hydrocarbons by bacteria.

Authors:  R A Kanaly; S Harayama
Journal:  J Bacteriol       Date:  2000-04       Impact factor: 3.490

2.  Kinetic Analysis: Benzo(a) pyrene in Southeastern Ohio.

Authors:  D Kolbow; H Hikichi; C Tuthill; C W Frank; G B Wiersma; A B Crockett; R D Schonbrod
Journal:  Environ Monit Assess       Date:  1986-05       Impact factor: 2.513

3.  Synergistic induction of AHR regulated genes in developmental toxicity from co-exposure to two model PAHs in zebrafish.

Authors:  Alicia R Timme-Laragy; Crystal J Cockman; Cole W Matson; Richard T Di Giulio
Journal:  Aquat Toxicol       Date:  2007-09-14       Impact factor: 4.964

4.  Kinetics and biotransformation of benzo(a)pyrene in Chironomus riparius.

Authors:  G J Leversee; J P Giesy; P F Landrum; S Gerould; J W Bowling; T E Fannin; J D Haddock; S M Bartell
Journal:  Arch Environ Contam Toxicol       Date:  1982       Impact factor: 2.804

Review 5.  Relationship between biotransformation and the toxicity and fate of xenobiotic chemicals in fish.

Authors:  J J Lech; J R Bend
Journal:  Environ Health Perspect       Date:  1980-02       Impact factor: 9.031

6.  State of research: environmental pathways and food chain transfer.

Authors:  B E Vaughan
Journal:  Environ Health Perspect       Date:  1984-03       Impact factor: 9.031

Review 7.  Cytochrome P-450 monooxygenase systems in aquatic species: carcinogen metabolism and biomarkers for carcinogen and pollutant exposure.

Authors:  J J Stegeman; J J Lech
Journal:  Environ Health Perspect       Date:  1991-01       Impact factor: 9.031

8.  Environmental fate of five radio-labeled coal conversion by-products evaluated in a laboratory model ecosystem.

Authors:  P Y Lu; R L Metcalf; E M Carlson
Journal:  Environ Health Perspect       Date:  1978-06       Impact factor: 9.031
  8 in total

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