Literature DB >> 20062883

Cellular uptake and binding of guanidine-modified phthalocyanines to KRAS/HRAS G-quadruplexes.

Alexandro Membrino1, Manikandan Paramasivam, Susanna Cogoi, Jawad Alzeer, Nathan W Luedtke, Luigi E Xodo.   

Abstract

Guanidino-modified phthalocyanines are evaluated in vitro (polymerase-stop assays and FRET) and in cultured cells as G4-DNA ligands and modulators of gene transcription.

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Year:  2009        PMID： 20062883     DOI： 10.1039/b918964e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  The KRAS promoter responds to Myc-associated zinc finger and poly(ADP-ribose) polymerase 1 proteins, which recognize a critical quadruplex-forming GA-element.

Authors:  Susanna Cogoi; Manikandan Paramasivam; Alexandro Membrino; Kazunari K Yokoyama; Luigi E Xodo
Journal:  J Biol Chem       Date:  2010-05-10       Impact factor: 5.157

2.  "One ring to bind them all"-part I: the efficiency of the macrocyclic scaffold for g-quadruplex DNA recognition.

Authors:  David Monchaud; Anton Granzhan; Nicolas Saettel; Aurore Guédin; Jean-Louis Mergny; Marie-Paule Teulade-Fichou
Journal:  J Nucleic Acids       Date:  2010-05-24

3.  RNA G-Quadruplexes in the model plant species Arabidopsis thaliana: prevalence and possible functional roles.

Authors:  Melissa A Mullen; Kalee J Olson; Paul Dallaire; François Major; Sarah M Assmann; Philip C Bevilacqua
Journal:  Nucleic Acids Res       Date:  2010-09-21       Impact factor: 16.971

4.  G4-DNA formation in the HRAS promoter and rational design of decoy oligonucleotides for cancer therapy.

Authors:  Alexandro Membrino; Susanna Cogoi; Erik B Pedersen; Luigi E Xodo
Journal:  PLoS One       Date:  2011-09-08       Impact factor: 3.240

5.  KRAS oncogene repression in colon cancer cell lines by G-quadruplex binding indolo[3,2-c]quinolines.

Authors:  João Lavrado; Hugo Brito; Pedro M Borralho; Stephan A Ohnmacht; Nam-Soon Kim; Clara Leitão; Sílvia Pisco; Mekala Gunaratnam; Cecília M P Rodrigues; Rui Moreira; Stephen Neidle; Alexandra Paulo
Journal:  Sci Rep       Date:  2015-04-08       Impact factor: 4.379

6.  Indoloquinoline-Mediated Targeted Downregulation of KRAS through Selective Stabilization of the Mid-Promoter G-Quadruplex Structure.

Authors:  Alexandra Maria Psaras; Rhianna K Carty; Jared T Miller; L Nathan Tumey; Tracy A Brooks
Journal:  Genes (Basel)       Date:  2022-08-13       Impact factor: 4.141

7.  Isolation and X-ray characterization of palladium-N complexes in the guanylation of aromatic amines. Mechanistic implications.

Authors:  Abdessamad Grirrane; Hermenegildo Garcia; Eleuterio Alvarez
Journal:  Beilstein J Org Chem       Date:  2013-07-22       Impact factor: 2.883

8.  An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex.

Authors:  Keiko Kawauchi; Wataru Sugimoto; Takatoshi Yasui; Kohei Murata; Katsuhiko Itoh; Kazuki Takagi; Takaaki Tsuruoka; Kensuke Akamatsu; Hisae Tateishi-Karimata; Naoki Sugimoto; Daisuke Miyoshi
Journal:  Nat Commun       Date:  2018-06-11       Impact factor: 14.919

Review 9.  Photosensitizers Based on G-Quadruplex Ligand for Cancer Photodynamic Therapy.

Authors:  Keiko Kawauchi; Ryoto Urano; Natsuki Kinoshita; Shin Kuwamoto; Takeru Torii; Yoshiki Hashimoto; Shinya Taniguchi; Mitsuki Tsuruta; Daisuke Miyoshi
Journal:  Genes (Basel)       Date:  2020-11-12       Impact factor: 4.096
  9 in total

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