Literature DB >> 20062839

Is the action spectrum for the UV-induced production of previtamin D3 in human skin correct?

Mary Norval1, Lars Olof Björn, Frank R de Gruijl.   

Abstract

The universally recognised action spectrum for the UV-induced conversion of 7-dehydrocholesterol to previtamin D(3) in human skin was published in 1982, and indicates a maximum at about 297 nm with essentially no production above 315 nm. This work represents a milestone in research on vitamin D, but limitations in the original data should be recognised. Various findings have arisen in recent years which cast doubts on the accuracy of the action spectrum and its application for spectral weighting in calculations of effective UV doses. In conclusion, the construction of an entirely new computational model to predict previtamin D levels is recommended.

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Year:  2009        PMID: 20062839     DOI: 10.1039/b9pp00012g

Source DB:  PubMed          Journal:  Photochem Photobiol Sci        ISSN: 1474-905X            Impact factor:   3.982


  16 in total

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Authors:  Merve Wollweber; Bernhard Roth
Journal:  Sensors (Basel)       Date:  2019-05-24       Impact factor: 3.576

Review 2.  Modulation of the immune system by UV radiation: more than just the effects of vitamin D?

Authors:  Prue H Hart; Shelley Gorman; John J Finlay-Jones
Journal:  Nat Rev Immunol       Date:  2011-08-19       Impact factor: 53.106

Review 3.  Skin cancer and vitamin D: an update.

Authors:  Candy Wyatt; Rachel E Neale; Robyn M Lucas
Journal:  Melanoma Manag       Date:  2015-02-25

4.  Sun and ski holidays improve vitamin D status, but are associated with high levels of DNA damage.

Authors:  Bibi Petersen; Hans C Wulf; Margarita Triguero-Mas; Peter A Philipsen; Elisabeth Thieden; Peter Olsen; Jakob Heydenreich; Payam Dadvand; Xavier Basagaña; Tove S Liljendahl; Graham I Harrison; Dan Segerbäck; Alois W Schmalwieser; Antony R Young; Mark J Nieuwenhuijsen
Journal:  J Invest Dermatol       Date:  2014-05-20       Impact factor: 8.551

5.  Lumisterol is metabolized by CYP11A1: discovery of a new pathway.

Authors:  Robert C Tuckey; Andrzej T Slominski; Chloe Y S Cheng; Jianjun Chen; Tae-Kang Kim; Min Xiao; Wei Li
Journal:  Int J Biochem Cell Biol       Date:  2014-08-13       Impact factor: 5.085

6.  Environmental effects of ozone depletion and its interactions with climate change: Progress report, 2016.

Authors: 
Journal:  Photochem Photobiol Sci       Date:  2017-02-15       Impact factor: 3.982

7.  Exposure to UV Wavelengths in Sunlight Suppresses Immunity. To What Extent is UV-induced Vitamin D3 the Mediator Responsible?

Authors:  Prue H Hart; Shelley Gorman
Journal:  Clin Biochem Rev       Date:  2013-02

8.  Seasonal variation of 25-Hydroxyvitamin D and indices of carbohydrate and lipid metabolism in postmenopausal women.

Authors:  Anna Huta-Osiecka; Krystian Wochna; Zbigniew Kasprzak; Alicja Nowak
Journal:  PeerJ       Date:  2021-05-13       Impact factor: 2.984

Review 9.  UV "Indices"-What Do They Indicate?

Authors:  Hanns Moshammer; Stana Simic; Daniela Haluza
Journal:  Int J Environ Res Public Health       Date:  2016-10-24       Impact factor: 3.390

10.  CYP27A1 acts on the pre-vitamin D3 photoproduct, lumisterol, producing biologically active hydroxy-metabolites.

Authors:  Robert C Tuckey; Wei Li; Dejian Ma; Chloe Y S Cheng; Katie M Wang; Tae-Kang Kim; Saowanee Jeayeng; Andrzej T Slominski
Journal:  J Steroid Biochem Mol Biol       Date:  2018-02-13       Impact factor: 4.292

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