Literature DB >> 20062550

Challenges of cellulitis in a lymphedematous extremity: a case report.

Matthew Pierce Connor1, Richard Gamelli.   

Abstract

INTRODUCTION: Lymphedema is a relatively common phenomenon. It is important that clinicians appreciate the relative risks imposed by this condition. While for some it may only represent a flaw in appearance, this condition can potentially have fatal consequences. Our case reports on the challenges of cellulitis in a lymphedematous extremity that progressed to septic shock. CASE
PRESENTATION: A 37-year-old Hispanic male was transferred to the Burn Unit from an outside hospital for wound care of an extremely severe case of cellulitis. He suffered massive lymphedema of his lower extremity, with innumerable nodules and chronic skin changes. After 3 days of cellulitis, he was in critical condition and required intubation and vasopressors. With intense wound care and systemic antibiotics, he gradually recovered and was discharged in 16 days with his cellulitis resolved and ambulating independently.
CONCLUSION: Our case highlights the special care and attention that chronic lymphedema deserves. These patients can exhibit marked disfigurement and physical disability affecting them on both social and physical levels. They also are at great medical risk, as cellulitis almost cost our patient his life. Evidence indicates that lymphedema, no matter the etiology, is susceptible to cellulitis with both great propensity and virulence. Physicians should be aware of the great risk of lymphedema, strive to prevent deterioration and complications, and be prepared to educate and closely monitor these patients.

Entities:  

Year:  2009        PMID: 20062550      PMCID: PMC2804019          DOI: 10.1186/1757-1626-2-9377

Source DB:  PubMed          Journal:  Cases J        ISSN: 1757-1626


  8 in total

1.  Risk factors for erysipelas of the leg (cellulitis): case-control study.

Authors:  A Dupuy; H Benchikhi; J C Roujeau; P Bernard; L Vaillant; O Chosidow; B Sassolas; J C Guillaume; J J Grob; S Bastuji-Garin
Journal:  BMJ       Date:  1999-06-12

2.  Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema.

Authors:  M J Karkkainen; R E Ferrell; E C Lawrence; M A Kimak; K L Levinson; M A McTigue; K Alitalo; D N Finegold
Journal:  Nat Genet       Date:  2000-06       Impact factor: 38.330

3.  Cellulitis complicating lymphoedema.

Authors:  P C Woo; P N Lum; S S Wong; V C Cheng; K Y Yuen
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2000-04       Impact factor: 3.267

4.  A case of cellulitis that complicated lymphedema of the lower limb and produced systemic inflammatory response syndrome (SIRS).

Authors:  A Kasai-Sakamoto; Y Yokoyama; H Mizunuma
Journal:  Eur J Gynaecol Oncol       Date:  2006       Impact factor: 0.196

Review 5.  Managing lymphedema.

Authors:  P S Mortimer
Journal:  Clin Dermatol       Date:  1995 Sep-Oct       Impact factor: 3.541

6.  Evidence for altered cell-mediated immunity in postmastectomy lymphoedema.

Authors:  E Mallon; S Powell; P Mortimer; T J Ryan
Journal:  Br J Dermatol       Date:  1997-12       Impact factor: 9.302

7.  Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome.

Authors:  J Fang; S L Dagenais; R P Erickson; M F Arlt; M W Glynn; J L Gorski; L H Seaver; T W Glover
Journal:  Am J Hum Genet       Date:  2000-11-08       Impact factor: 11.025

Review 8.  Lower extremity lymphedema update: pathophysiology, diagnosis, and treatment guidelines.

Authors:  Katherine Kerchner; Anne Fleischer; Gil Yosipovitch
Journal:  J Am Acad Dermatol       Date:  2008-05-29       Impact factor: 11.527

  8 in total
  2 in total

1.  A Prospective Study on the Safety and Efficacy of Vascularized Lymph Node Transplant.

Authors:  Stav Brown; Babak J Mehrara; Michelle Coriddi; Leslie McGrath; Michele Cavalli; Joseph H Dayan
Journal:  Ann Surg       Date:  2022-07-15       Impact factor: 13.787

Review 2.  Histopathologic Features of Lymphedema: A Molecular Review.

Authors:  Claire Y Li; Raghu P Kataru; Babak J Mehrara
Journal:  Int J Mol Sci       Date:  2020-04-06       Impact factor: 5.923

  2 in total

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