Literature DB >> 20062038

Putting the lid on phosphodiesterase 4.

Miles D Houslay, David R Adams.   

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Year:  2010        PMID： 20062038     DOI： 10.1038/nbt0110-38

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  12 in total

1.  UCR1 and UCR2 domains unique to the cAMP-specific phosphodiesterase family form a discrete module via electrostatic interactions.

Authors:  M B Beard; A E Olsen; R E Jones; S Erdogan; M D Houslay; G B Bolger
Journal:  J Biol Chem       Date:  2000-04-07       Impact factor: 5.157

Review 2.  Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling.

Authors:  Marco Conti; Joseph Beavo
Journal:  Annu Rev Biochem       Date:  2007       Impact factor: 23.643

3.  Scanning peptide array analyses identify overlapping binding sites for the signalling scaffold proteins, beta-arrestin and RACK1, in cAMP-specific phosphodiesterase PDE4D5.

Authors:  Graeme B Bolger; George S Baillie; Xiang Li; Martin J Lynch; Pawel Herzyk; Ahmed Mohamed; Lisa High Mitchell; Angela McCahill; Christian Hundsrucker; Enno Klussmann; David R Adams; Miles D Houslay
Journal:  Biochem J       Date:  2006-08-15       Impact factor: 3.857

4.  Activation of the cAMP-specific phosphodiesterase PDE4D3 by phosphorylation. Identification and function of an inhibitory domain.

Authors:  J Lim; G Pahlke; M Conti
Journal:  J Biol Chem       Date:  1999-07-09       Impact factor: 5.157

5.  Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B. Consequences for rolipram inhibition.

Authors:  I McPhee; S J Yarwood; G Scotland; E Huston; M B Beard; A H Ross; E S Houslay; M D Houslay
Journal:  J Biol Chem       Date:  1999-04-23       Impact factor: 5.157

6.  Deletion of phosphodiesterase 4D in mice shortens alpha(2)-adrenoceptor-mediated anesthesia, a behavioral correlate of emesis.

Authors:  Annette Robichaud; Panagiota B Stamatiou; S-L Catherine Jin; Nicholas Lachance; Dwight MacDonald; France Laliberté; Susana Liu; Zheng Huang; Marco Conti; Chi-Chung Chan
Journal:  J Clin Invest       Date:  2002-10       Impact factor: 14.808

7.  Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity.

Authors:  R X Xu; A M Hassell; D Vanderwall; M H Lambert; W D Holmes; M A Luther; W J Rocque; M V Milburn; Y Zhao; H Ke; R T Nolte
Journal:  Science       Date:  2000-06-09       Impact factor: 47.728

Review 8.  cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling.

Authors:  Miles D Houslay; George S Baillie; Donald H Maurice
Journal:  Circ Res       Date:  2007-04-13       Impact factor: 17.367

9.  Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety.

Authors:  Alex B Burgin; Olafur T Magnusson; Jasbir Singh; Pam Witte; Bart L Staker; Jon M Bjornsson; Margret Thorsteinsdottir; Sigrun Hrafnsdottir; Timothy Hagen; Alex S Kiselyov; Lance J Stewart; Mark E Gurney
Journal:  Nat Biotechnol       Date:  2009-12-27       Impact factor: 54.908

Review 10.  Keynote review: phosphodiesterase-4 as a therapeutic target.

Authors:  Miles D Houslay; Peter Schafer; Kam Y J Zhang
Journal:  Drug Discov Today       Date:  2005-11-15       Impact factor: 7.851
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  12 in total

Review 1.  Advances in targeting cyclic nucleotide phosphodiesterases.

Authors:  Donald H Maurice; Hengming Ke; Faiyaz Ahmad; Yousheng Wang; Jay Chung; Vincent C Manganiello
Journal:  Nat Rev Drug Discov       Date:  2014-04       Impact factor: 84.694

2.  Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4.

Authors:  Peder Cedervall; Ann Aulabaugh; Kieran F Geoghegan; Thomas J McLellan; Jayvardhan Pandit
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-09       Impact factor: 11.205

3.  An evolutionary analysis of cAMP-specific Phosphodiesterase 4 alternative splicing.

Authors:  Keven R Johnson; Jessie Nicodemus-Johnson; Robert S Danziger
Journal:  BMC Evol Biol       Date:  2010-08-11       Impact factor: 3.260

4.  Disease progression in MRL/lpr lupus-prone mice is reduced by NCS 613, a specific cyclic nucleotide phosphodiesterase type 4 (PDE4) inhibitor.

Authors:  Thérèse Keravis; Fanny Monneaux; Issaka Yougbaré; Lucien Gazi; Jean-Jacques Bourguignon; Sylviane Muller; Claire Lugnier
Journal:  PLoS One       Date:  2012-01-11       Impact factor: 3.240

5.  The putative tumor suppressor VILIP-1 counteracts epidermal growth factor-induced epidermal-mesenchymal transition in squamous carcinoma cells.

Authors:  Katharina Schönrath; Andres J Klein-Szanto; Karl H Braunewell
Journal:  PLoS One       Date:  2012-03-30       Impact factor: 3.240

6.  Dimerization of cAMP phosphodiesterase-4 (PDE4) in living cells requires interfaces located in both the UCR1 and catalytic unit domains.

Authors:  Graeme B Bolger; Allan J Dunlop; Dong Meng; Jon P Day; Enno Klussmann; George S Baillie; David R Adams; Miles D Houslay
Journal:  Cell Signal       Date:  2014-12-27       Impact factor: 4.315

7.  Therapeutic benefits of phosphodiesterase 4B inhibition after traumatic brain injury.

Authors:  Nicole M Wilson; Mark E Gurney; W Dalton Dietrich; Coleen M Atkins
Journal:  PLoS One       Date:  2017-05-19       Impact factor: 3.240

Review 8.  Targeting phosphodiesterase 4 as a potential therapeutic strategy for enhancing neuroplasticity following ischemic stroke.

Authors:  Haitao Wang; Uma Gaur; Jiao Xiao; Bingtian Xu; Jiangping Xu; Wenhua Zheng
Journal:  Int J Biol Sci       Date:  2018-10-03       Impact factor: 6.580

9.  Epac and the high affinity rolipram binding conformer of PDE4 modulate neurite outgrowth and myelination using an in vitro spinal cord injury model.

Authors:  S D Boomkamp; M A McGrath; M D Houslay; S C Barnett
Journal:  Br J Pharmacol       Date:  2014-05       Impact factor: 8.739

Review 10.  The Molecular Basis for Specificity at the Level of the Protein Kinase a Catalytic Subunit.

Authors:  Kristoffer Søberg; Bjørn Steen Skålhegg
Journal:  Front Endocrinol (Lausanne)       Date:  2018-09-12       Impact factor: 5.555
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