Literature DB >> 20060885

Experimental approaches to the study of epigenomic dysregulation in ageing.

Reid F Thompson1, Melissa J Fazzari, John M Greally.   

Abstract

In this review, we describe how normal ageing may involve the acquisition of epigenetic errors over time, akin to the accumulation of genetic mutations with ageing. We describe how such experiments are currently performed, their limitations technically and analytically and their application to ageing research. 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20060885      PMCID： PMC2838972          DOI： 10.1016/j.exger.2009.12.013

Source DB:  PubMed          Journal:  Exp Gerontol        ISSN： 0531-5565            Impact factor:   4.032


  225 in total

1.  McrBC: a multisubunit GTP-dependent restriction endonuclease.

Authors:  E Sutherland; L Coe; E A Raleigh
Journal:  J Mol Biol       Date:  1992-05-20       Impact factor: 5.469

2.  A genomic sequencing protocol that yields a positive display of 5-methylcytosine residues in individual DNA strands.

Authors:  M Frommer; L E McDonald; D S Millar; C M Collis; F Watt; G W Grigg; P L Molloy; C L Paul
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205

Review 3.  CpG-rich islands and the function of DNA methylation.

Authors:  A P Bird
Journal:  Nature       Date:  1986 May 15-21       Impact factor: 49.962

Review 4.  A third component causing random variability beside environment and genotype. A reason for the limited success of a 30 year long effort to standardize laboratory animals?

Authors:  K Gärtner
Journal:  Lab Anim       Date:  1990-01       Impact factor: 2.471

5.  Methylation profiles of genomic DNA of mouse developmental brain detected by restriction landmark genomic scanning (RLGS) method.

Authors:  J Kawai; S Hirotsune; K Hirose; S Fushiki; S Watanabe; Y Hayashizaki
Journal:  Nucleic Acids Res       Date:  1993-12-11       Impact factor: 16.971

6.  The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression.

Authors:  P Jeppesen; B M Turner
Journal:  Cell       Date:  1993-07-30       Impact factor: 41.582

7.  Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin.

Authors:  V Orlando; R Paro
Journal:  Cell       Date:  1993-12-17       Impact factor: 41.582

8.  The in vitro lifespan of MRC-5 cells is shortened by 5-azacytidine-induced demethylation.

Authors:  D S Fairweather; M Fox; G P Margison
Journal:  Exp Cell Res       Date:  1987-01       Impact factor: 3.905

9.  Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl-CpG binding protein.

Authors:  J Boyes; A Bird
Journal:  EMBO J       Date:  1992-01       Impact factor: 11.598

10.  A direct link between core histone acetylation and transcriptionally active chromatin.

Authors:  T R Hebbes; A W Thorne; C Crane-Robinson
Journal:  EMBO J       Date:  1988-05       Impact factor: 11.598
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  5 in total

1.  Lysine-specific demethylase-1 modifies the age effect on blood pressure sensitivity to dietary salt intake.

Authors:  Alexander W Krug; Eric Tille; Bei Sun; Luminita Pojoga; Jonathan Williams; Bindu Chamarthi; Andrew H Lichtman; Paul N Hopkins; Gail K Adler; Gordon H Williams
Journal:  Age (Dordr)       Date:  2012-10-02

Review 2.  Kidney and epigenetic mechanisms of salt-sensitive hypertension.

Authors:  Wakako Kawarazaki; Toshiro Fujita
Journal:  Nat Rev Nephrol       Date:  2021-02-24       Impact factor: 28.314

3.  Molecular marks for epigenetic identification of developmental and cancer stem cells.

Authors:  Samir Kumar Patra; Moonmoon Deb; Aditi Patra
Journal:  Clin Epigenetics       Date:  2010-12-17       Impact factor: 6.551

4.  DNA methylation outlier burden, health, and ageing in Generation Scotland and the Lothian Birth Cohorts of 1921 and 1936.

Authors:  Anne Seeboth; Daniel L McCartney; Yunzhang Wang; Robert F Hillary; Anna J Stevenson; Rosie M Walker; Archie Campbell; Kathryn L Evans; Andrew M McIntosh; Sara Hägg; Ian J Deary; Riccardo E Marioni
Journal:  Clin Epigenetics       Date:  2020-03-26       Impact factor: 6.551

Review 5.  DNA methylation aging clocks: challenges and recommendations.

Authors:  Christopher G Bell; Robert Lowe; Peter D Adams; Andrea A Baccarelli; Stephan Beck; Jordana T Bell; Brock C Christensen; Vadim N Gladyshev; Bastiaan T Heijmans; Steve Horvath; Trey Ideker; Jean-Pierre J Issa; Karl T Kelsey; Riccardo E Marioni; Wolf Reik; Caroline L Relton; Leonard C Schalkwyk; Andrew E Teschendorff; Wolfgang Wagner; Kang Zhang; Vardhman K Rakyan
Journal:  Genome Biol       Date:  2019-11-25       Impact factor: 13.583
  5 in total

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