Literature DB >> 20060715

Synthesis, in vitro and in vivo studies of Gd-DTPA-XDA-D1-Glc(OH) complex as a new potential MRI contrast agent.

Nobuhisa Ozaki1, Arigala Uma Ravi Sankar, Mitsuji Yamashita, Takashi Aoki, Yasutaka Tanaka, Motohiko Kimura, Mitsuo Toda, Michio Fujie, Yasuo Takehara, Harumi Sakahara.   

Abstract

A new type of dendritic molecules Gd-DTPA-XDA-D1-Glc(OH), which work as a functionalized ligand coordinating gadolinium(III) ion at the center of their frameworks with two glucose moieties on the molecular surfaces, were readily synthesized with high yield. The structures were established by IR, (1)H, (13)C NMR, and mass spectral studies. Its bio-distribution patterns were evaluated on rats. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID: 20060715     DOI: 10.1016/j.bmcl.2009.12.067

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

Review 1.  Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.

Authors:  David J Harvey
Journal:  Mass Spectrom Rev       Date:  2014-05-26       Impact factor: 10.946

2.  Spectrophotometric determination and removal of unchelated europium ions from solutions containing Eu-diethylenetriaminepentaacetic acid chelate-peptide conjugates.

Authors:  N G R Dayan Elshan; Renata Patek; Josef Vagner; Eugene A Mash
Journal:  Anal Biochem       Date:  2014-07-21       Impact factor: 3.365

  2 in total

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