| Literature DB >> 20060700 |
Takaya Maruyama1, Esteban C Gabazza, John Morser, Takehiro Takagi, Corina D'Alessandro-Gabazza, Shizu Hirohata, Sei Nakayama, Alexis Y Ramirez, Atsushi Fujiwara, Masahiro Naito, Kimiaki Nishikubo, Hisamichi Yuda, Masamichi Yoshida, Yoshiyuki Takei, Osamu Taguchi.
Abstract
The rapid increase in the elderly population is leading to a corresponding increase in the number of people requiring medical care. To date no comparative study between community-acquired pneumonia (CAP) and nursing home-acquired pneumonia (NHAP) has been reported in the very elderly non-intubated patients. The present study was undertaken to compare the clinical characteristics and microbial etiology between CAP and NHAP in elderly patients >/=85-years old. There were 54 patients with NHAP and 47 with CAP. Performance status was significantly worse in the NHAP than in the CAP group. Among all patients, the most frequent pathogens were Chlamydophilia pneumoniae followed by Streptococcus pneumoniae, Mycoplasma pneumoniae influenza virus and Staphylococcus aureus. The frequency of S. peumoniae was significantly higher in NHAP patients than in CAP patients after adjusting for age and sex. Physical activity, nutrition status and dehydration were significant prognostic factors of pneumonia among all patients. In-hospital mortality was significantly higher in NHAP than in CAP after adjusting for age and sex. This study demonstrated that the etiology and clinical outcome differ between CAP and NHAP patients in the very elderly non-intubated population. Copyright 2010 Elsevier Ltd. All rights reserved.Entities:
Mesh：
Year: 2010 PMID： 20060700 DOI： 10.1016/j.rmed.2009.12.008
Source DB: PubMed Journal: Respir Med ISSN： 0954-6111 Impact factor: 3.415