Literature DB >> 2006068

An audit of anticoagulation and endocarditis prophylaxis after heart valve surgery.

M A Fitzpatrick1, F McCone.   

Abstract

OBJECTIVE: to audit anticoagulant control and endocarditis prophylaxis following heart valve surgery.
DESIGN: retrospective review of all 190 patients living in Canterbury who had heart valve surgery between January 1981 and December 1986 to determine the incidence of endocarditis and complications of anticoagulation.
RESULTS: there were 35 late deaths, of which nine were attributed to thromboembolism (3), major bleeding (2), or endocarditis (4). The rate of thromboembolic events, and major bleeding was 4.6 and 3.3/100 patient years of warfarin therapy respectively, while the incidence of late endocarditis was 0.96/100 patient years. Two episodes of endocarditis occurred after minor dental procedures performed without antibiotic prophylaxis. Many dentists indicated that they would not have recommended prophylactic therapy for these procedures. Some patients had inadequate recall of important details of anticoagulant control or endocarditis prophylaxis. Only 24% knew their latest prothrombin ratio, yet a survey of general practitioners revealed that, in their view, the majority of patients may be capable of monitoring their own anticoagulant therapy.
CONCLUSION: the incidence of potentially preventable long term complications of heart valve surgery is comparable to other series. Nevertheless, these complications could be reduced by better patient education possibly enhanced by greater involvement of the patient in their anticoagulant control. The indications for antibiotic prophylaxis for dental procedures should be broadened for this group of patients.

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Year:  1991        PMID: 2006068

Source DB:  PubMed          Journal:  N Z Med J        ISSN: 0028-8446


  3 in total

1.  Economic constraints and prescribing patterns in New Zealand.

Authors:  G S Kellaway
Journal:  Pharmacoeconomics       Date:  1992-09       Impact factor: 4.981

Review 2.  Drug treatment associated with heart valve replacement.

Authors:  D S Coulshed; M A Fitzpatrick; C H Lee
Journal:  Drugs       Date:  1995-06       Impact factor: 9.546

Review 3.  Safety of treatment with oral anticoagulants in the elderly. A systematic review.

Authors:  B A Hutten; A W Lensing; R A Kraaijenhagen; M H Prins
Journal:  Drugs Aging       Date:  1999-04       Impact factor: 3.923

  3 in total

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