| Literature DB >> 20060315 |
Shenheng Guan1, Alma L Burlingame.
Abstract
Stored waveform inverse Fourier transform (SWIFT) technology has been implemented on a commercial Fourier transform ICR mass spectrometer. Complex ejection/isolation waveforms can be generated on an arbitrary waveform generator (AWG) and applied to the instrument by use of a high speed analog switch. High mass selectivity and subsequent electron capture dissociation (ECD) of the SWIFT isolated ions has been demonstrated with analysis of intact Bovine histone H4. A mass selectivity about 0.1 m/z unit for isolation of the 18+ charge state ions was achieved. Adaptation of SWIFT on the commercial instrument provides an enhanced capability for characterizing intact proteins by top-down analysis. Copyright 2010 American Society for Mass Spectrometry. Published by Elsevier Inc. All rights reserved.Entities:
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Year: 2009 PMID: 20060315 PMCID: PMC3384707 DOI: 10.1016/j.jasms.2009.11.011
Source DB: PubMed Journal: J Am Soc Mass Spectrom ISSN: 1044-0305 Impact factor: 3.109