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Literature DB >> 200602

Direct selective procedure for isolating Neurospora mutants defective in nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase.

Abstract

A procedure has been developed for isolating nicotinamide adenine dinucleotide phosphate-specific glutamate dehydrogenase (am) mutants of Neurospora. Physiological, genetic, and enzymatic tests show that the new mutants are am alleles. Reconstruction tests and analysis of the new alleles show that the procedure yields a broad spectrum of lesions at the am locus. The isolation of am mutants by this technique appears to be related to the effect of am mutants on the control of the general permease.

Entities: Chemical

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Year: 1977 PMID： 200602 PMCID： PMC235574 DOI： 10.1128/jb.132.3.751-756.1977

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

12 in total

1. Mutational amino acid replacements in Neurospora crassa NADP-specific glutamate dehydrogenase.

Authors: M Brett; G K Chambers; A A Holder; J R Fincham; J C Wootton
Journal: J Mol Biol Date: 1976-09-05 Impact factor: 5.469

2. IMMUNOLOGICAL STUDIES OF AMINATION DEFICIENT STRAINS OF NEUROSPORA CRASSIA.

Authors: D B ROBERTS; J A PATEMAN
Journal: J Gen Microbiol Date: 1964-02

3. MUTATIONAL ALTERATION OF PERMEABILITY IN NEUROSPORA: EFFECTS ON GROWTH AND THE UPTAKE OF CERTAIN AMINO ACIDS AND RELATED COMPOUNDS.

Authors: P STLAWRENCE; B D MALING; L ALTWERGER; M RACHMELER
Journal: Genetics Date: 1964-12 Impact factor: 4.562

4. COMPLEMENTATION RELATIONSHIP OF NEUROSPORA AM MUTANTS IN RELATION TO THEIR FORMATION OF ABNORMAL VARIETIES OF GLUTAMATE DEHYDROGENASE.

Authors: J R FINCHAM; D R STADLER
Journal: Genet Res Date: 1965-02 Impact factor: 1.588

5. Purification and characterization of a TPN-specific glutamic acid dehydrogenase Neurospora crassa.

Authors: R W BARRATT; W N STRICKLAND
Journal: Arch Biochem Biophys Date: 1963-07 Impact factor: 4.013

6. Ammonia inhibition of the general amino acid permease and its suppression in NADPH-specific glutamate dehydrogenaseless mutants of saccharomyces cerevisiae.

Authors: M Grenson; C Hou
Journal: Biochem Biophys Res Commun Date: 1972-08-21 Impact factor: 3.575

7. A new map of the amination-1 locus of Neurospora crassa, and the effect of the recombination-3 gene.

Authors: D R Smyth
Journal: Aust J Biol Sci Date: 1973-12

8. Reversion of the am locus in Neurospora: evidence for nonsense suppression.

Authors: T Seale
Journal: Genetics Date: 1968-01 Impact factor: 4.562

9. Amino acid transport in Neurospora crassa. II. Properties of a basic amino acid transport system.

Authors: M L Pall
Journal: Biochim Biophys Acta Date: 1970-03-17

10. Suppressors of amino acid uptake mutants of Neurospora.

Authors: D R Stadler
Journal: Genetics Date: 1967-12 Impact factor: 4.562

9 in total

1. An unstable allele of the am locus of Neurospora crassa.

Authors: J A Kinsey; J R Fincham
Journal: Genetics Date: 1979-11 Impact factor: 4.562

2. Isolation of a transposable element from Neurospora crassa.

Authors: J A Kinsey; J Helber
Journal: Proc Natl Acad Sci U S A Date: 1989-03 Impact factor: 11.205

3. Mutation at the am locus of Neurospora crassa.

Authors: J A Kinsey; B S Hung
Journal: Genetics Date: 1981 Nov-Dec Impact factor: 4.562

Review 4. Chromosomal loci of Neurospora crassa.

Authors: D D Perkins; A Radford; D Newmeyer; M Björkman
Journal: Microbiol Rev Date: 1982-12

5. Genetic and enzymatic characterization of the inducible glycerol dissimilatory system of Neurospora crassa.

Authors: P F Denor; J B Courtright
Journal: J Bacteriol Date: 1982-08 Impact factor: 3.490

6. Nitrogen control of Salmonella typhimurium: co-regulation of synthesis of glutamine synthetase and amino acid transport systems.

Authors: S G Kustu; N C McFarland; S P Hui; B Esmon; G F Ames
Journal: J Bacteriol Date: 1979-04 Impact factor: 3.490