Literature DB >> 20059210

Unpinning of a spiral wave anchored around a circular obstacle by an external wave train: common aspects of a chemical reaction and cardiomyocyte tissue.

Masanobu Tanaka1, Akihiro Isomura, Marcel Hörning, Hiroyuki Kitahata, Konstantin Agladze, Kenichi Yoshikawa.   

Abstract

It is well known that spiral waves are often stabilized by anchoring to a local heterogeneity ("pinning") and that such pinned waves are rather difficult to eliminate. In the present report, we show that pinned spiral waves can be eliminated through collision with a wave train arriving from the outer region, as confirmed in experiments on the Belousov-Zhabotinsky (BZ) reaction as well as in cardiomyocyte tissue culture. A numerical simulation using the Oregonator, a mathematical model for the BZ reaction, provides the parameter area for successful unpinning. The scenario of unpinning is discussed in terms of the dispersion relation of the wave train by taking into account the curvature effect of the excitation wave.

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Year:  2009        PMID: 20059210     DOI: 10.1063/1.3263167

Source DB:  PubMed          Journal:  Chaos        ISSN: 1054-1500            Impact factor:   3.642


  4 in total

1.  Attraction and repulsion of spiral waves by inhomogeneity of conduction anisotropy--a model of spiral wave interaction with electrical remodeling of heart tissue.

Authors:  Pawel Kuklik; Prashanthan Sanders; Lukasz Szumowski; Jan J Żebrowski
Journal:  J Biol Phys       Date:  2012-10-07       Impact factor: 1.365

2.  Removal of pinned scroll waves in cardiac tissues by electric fields in a generic model of three-dimensional excitable media.

Authors:  De-Bei Pan; Xiang Gao; Xia Feng; Jun-Ting Pan; Hong Zhang
Journal:  Sci Rep       Date:  2016-02-24       Impact factor: 4.379

3.  Human Pluripotent Stem Cell-Derived Cardiac Tissue-like Constructs for Repairing the Infarcted Myocardium.

Authors:  Junjun Li; Itsunari Minami; Motoko Shiozaki; Leqian Yu; Shin Yajima; Shigeru Miyagawa; Yuji Shiba; Nobuhiro Morone; Satsuki Fukushima; Momoko Yoshioka; Sisi Li; Jing Qiao; Xin Li; Lin Wang; Hidetoshi Kotera; Norio Nakatsuji; Yoshiki Sawa; Yong Chen; Li Liu
Journal:  Stem Cell Reports       Date:  2017-10-26       Impact factor: 7.765

Review 4.  Mathematical approach to unpinning of spiral waves anchored to an obstacle with high-frequency pacing.

Authors:  Hiroyuki Kitahata; Masanobu Tanaka
Journal:  Biophys Physicobiol       Date:  2018-09-12
  4 in total

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