Literature DB >> 2005911

Transcriptional suppression of cellular gene expression by c-Myc.

B S Yang1, T J Geddes, R J Pogulis, B de Crombrugghe, S O Freytag.   

Abstract

High levels of c-Myc in mouse 3T3-L1 cells specifically suppress the expression of three collagen genes. This effect is exerted through collagen promoter sequences and requires the leucine zipper motif of c-Myc. Our data suggest that an important aspect of c-Myc transforming activity is the ability to suppress specific cellular gene transcription.

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Year:  1991        PMID： 2005911      PMCID： PMC359932          DOI： 10.1128/mcb.11.4.2291-2295.1991

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  35 in total

1.  Definition of the activities and properties of c-myc required to inhibit cell differentiation.

Authors:  S O Freytag; C V Dang; W M Lee
Journal:  Cell Growth Differ       Date:  1990-07

2.  N-myc amplification causes down-modulation of MHC class I antigen expression in neuroblastoma.

Authors:  R Bernards; S K Dessain; R A Weinberg
Journal:  Cell       Date:  1986-12-05       Impact factor: 41.582

3.  Regulation of a collagen gene promoter by the product of viral mos oncogene.

Authors:  A Schmidt; C Setoyama; B de Crombrugghe
Journal:  Nature       Date:  1985 Mar 21-27       Impact factor: 49.962

4.  Differential binding of a CCAAT DNA binding factor to the promoters of the mouse alpha 2(I) and alpha 1(III) collagen genes.

Authors:  A Hatamochi; B Paterson; B de Crombrugghe
Journal:  J Biol Chem       Date:  1986-08-25       Impact factor: 5.157

5.  An established pre-adipose cell line and its differentiation in culture.

Authors:  H Green; M Meuth
Journal:  Cell       Date:  1974-10       Impact factor: 41.582

6.  Regulation of heat shock protein 70 gene expression by c-myc.

Authors:  R E Kingston; A S Baldwin; P A Sharp
Journal:  Nature       Date:  1984 Nov 15-21       Impact factor: 49.962

7.  Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation.

Authors:  E V Prochownik; J Kukowska
Journal:  Nature       Date:  1986 Aug 28-Sep 3       Impact factor: 49.962

8.  Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

Authors:  C M Gorman; L F Moffat; B H Howard
Journal:  Mol Cell Biol       Date:  1982-09       Impact factor: 4.272

9.  Isolation of monoclonal antibodies specific for human c-myc proto-oncogene product.

Authors:  G I Evan; G K Lewis; G Ramsay; J M Bishop
Journal:  Mol Cell Biol       Date:  1985-12       Impact factor: 4.272

10.  Identification of a set of genes expressed during the G0/G1 transition of cultured mouse cells.

Authors:  L F Lau; D Nathans
Journal:  EMBO J       Date:  1985-12-01       Impact factor: 11.598
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  17 in total

1.  Identification of putative c-Myc-responsive genes: characterization of rcl, a novel growth-related gene.

Authors:  B C Lewis; H Shim; Q Li; C S Wu; L A Lee; A Maity; C V Dang
Journal:  Mol Cell Biol       Date:  1997-09       Impact factor: 4.272

2.  A point mutation in the MyoD basic domain imparts c-Myc-like properties.

Authors:  M E Van Antwerp; D G Chen; C Chang; E V Prochownik
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-01       Impact factor: 11.205

3.  Regulation of collagen I gene expression by ras.

Authors:  J L Slack; M I Parker; V R Robinson; P Bornstein
Journal:  Mol Cell Biol       Date:  1992-10       Impact factor: 4.272

4.  The impact of C-MYC gene expression on gastric cancer cell.

Authors:  Lin Zhang; Yanhong Hou; Hassan Ashktorab; Liucun Gao; Yanjie Xu; Kai Wu; Junshan Zhai; Lei Zhang
Journal:  Mol Cell Biochem       Date:  2010-08-25       Impact factor: 3.396

5.  An alternative pathway for gene regulation by Myc.

Authors:  K Peukert; P Staller; A Schneider; G Carmichael; F Hänel; M Eilers
Journal:  EMBO J       Date:  1997-09-15       Impact factor: 11.598

6.  BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo.

Authors:  Krishan Kumar; Brian T DeCant; Paul J Grippo; Rosa F Hwang; David J Bentrem; Kazumi Ebine; Hidayatullah G Munshi
Journal:  JCI Insight       Date:  2017-02-09

Review 7.  c-Myc target genes involved in cell growth, apoptosis, and metabolism.

Authors:  C V Dang
Journal:  Mol Cell Biol       Date:  1999-01       Impact factor: 4.272

8.  Overexpression of Myc suppresses CCAAT transcription factor/nuclear factor 1-dependent promoters in vivo.

Authors:  B S Yang; J D Gilbert; S O Freytag
Journal:  Mol Cell Biol       Date:  1993-05       Impact factor: 4.272

9.  Repression of cyclin D1: a novel function of MYC.

Authors:  A Philipp; A Schneider; I Väsrik; K Finke; Y Xiong; D Beach; K Alitalo; M Eilers
Journal:  Mol Cell Biol       Date:  1994-06       Impact factor: 4.272

10.  Transcriptional suppression of HLA-B expression by c-Myc is mediated through the core promoter elements.

Authors:  L T Peltenburg; P I Schrier
Journal:  Immunogenetics       Date:  1994       Impact factor: 2.846
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