Literature DB >> 20058198

Developments and challenges in human embryonic stem cell research in Spain.

R P Cervera1, M Stojkovic.   

Abstract

After years of following the trail of others, Spain is finally making a serious bid in science, specifically in regenerative medicine. In the framework of the European Union, Spain is setting up the basis for a solid collaborative network between public and private institutions, involving basic, translational, applied, technological and clinical researchers. In a society characterised by the idiom "slow but secure", it is still too soon to see the results of the huge economic and infrastructure investment made. We present here an overview of the challenges that have been surmounted and the ones that will have to be solved in order to situate Spain as a reference country in regenerative medicine worldwide.

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Year:  2009        PMID: 20058198     DOI: 10.1007/s12015-009-9093-x

Source DB:  PubMed          Journal:  Stem Cell Rev Rep        ISSN: 2629-3277            Impact factor:   5.739


  17 in total

1.  Molecular correlates of primate nuclear transfer failures.

Authors:  Calvin Simerly; Tanja Dominko; Christopher Navara; Christopher Payne; Saverio Capuano; Gabriella Gosman; Kowit-Yu Chong; Diana Takahashi; Crista Chace; Duane Compton; Laura Hewitson; Gerald Schatten
Journal:  Science       Date:  2003-04-11       Impact factor: 47.728

2.  Viable offspring derived from fetal and adult mammalian cells.

Authors:  I Wilmut; A E Schnieke; J McWhir; A J Kind; K H Campbell
Journal:  Nature       Date:  1997-02-27       Impact factor: 49.962

3.  Derivation of a human blastocyst after heterologous nuclear transfer to donated oocytes.

Authors:  Miodrag Stojkovic; Petra Stojkovic; Christine Leary; Vanessa Jane Hall; Lyle Armstrong; Mary Herbert; Maria Nesbitt; Majlinda Lako; Alison Murdoch
Journal:  Reprod Biomed Online       Date:  2005-08       Impact factor: 3.828

4.  Correction of a genetic defect by nuclear transplantation and combined cell and gene therapy.

Authors:  William M Rideout; Konrad Hochedlinger; Michael Kyba; George Q Daley; Rudolf Jaenisch
Journal:  Cell       Date:  2002-04-05       Impact factor: 41.582

5.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

6.  Development of human cloned blastocysts following somatic cell nuclear transfer with adult fibroblasts.

Authors:  Andrew J French; Catharine A Adams; Linda S Anderson; John R Kitchen; Marcus R Hughes; Samuel H Wood
Journal:  Stem Cells       Date:  2008-01-17       Impact factor: 6.277

7.  Embryonic stem cell lines derived from human blastocysts.

Authors:  J A Thomson; J Itskovitz-Eldor; S S Shapiro; M A Waknitz; J J Swiergiel; V S Marshall; J M Jones
Journal:  Science       Date:  1998-11-06       Impact factor: 47.728

8.  Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells.

Authors:  Angel Raya; Ignasi Rodríguez-Pizà; Guillermo Guenechea; Rita Vassena; Susana Navarro; María José Barrero; Antonella Consiglio; Maria Castellà; Paula Río; Eduard Sleep; Federico González; Gustavo Tiscornia; Elena Garreta; Trond Aasen; Anna Veiga; Inder M Verma; Jordi Surrallés; Juan Bueren; Juan Carlos Izpisúa Belmonte
Journal:  Nature       Date:  2009-05-31       Impact factor: 49.962

9.  Differentiation of human embryonic stem cells to regional specific neural precursors in chemically defined medium conditions.

Authors:  Slaven Erceg; Sergio Laínez; Mohammad Ronaghi; Petra Stojkovic; Maria Amparo Pérez-Aragó; Victoria Moreno-Manzano; Rubén Moreno-Palanques; Rosa Planells-Cases; Miodrag Stojkovic
Journal:  PLoS One       Date:  2008-05-07       Impact factor: 3.240

10.  Cancer genes hypermethylated in human embryonic stem cells.

Authors:  Vincenzo Calvanese; Angelica Horrillo; Abdelkrim Hmadcha; Beatriz Suarez-Alvarez; Agustín F Fernandez; Ester Lara; Sara Casado; Pablo Menendez; Clara Bueno; Javier Garcia-Castro; Ruth Rubio; Pablo Lapunzina; Miguel Alaminos; Lodovica Borghese; Stefanie Terstegge; Neil J Harrison; Harry D Moore; Oliver Brüstle; Carlos Lopez-Larrea; Peter W Andrews; Bernat Soria; Manel Esteller; Mario F Fraga
Journal:  PLoS One       Date:  2008-09-29       Impact factor: 3.240

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