Literature DB >> 20058109

Natural course of asymptomatic deep venous thrombosis in hip surgery without pharmacologic thromboprophylaxis in an Asian population.

Kosuke Tsuda1, Tomio Kawasaki, Nobuo Nakamura, Hideki Yoshikawa, Nobuhiko Sugano.   

Abstract

BACKGROUND: The clinical importance of asymptomatic deep venous thrombosis in elective hip surgery is not clearly known. QUESTIONS/PURPOSES: We determined the preoperative and postoperative incidences of asymptomatic deep venous thrombosis, identified preoperative factors associated with postoperative deep venous thrombosis or pulmonary embolism, and established its natural course in patients who underwent elective hip surgery without receiving pharmacologic thromboprophylaxis. PATIENTS AND METHODS: We reviewed 184 patients who underwent consecutive elective hip surgeries with a mechanical thromboprophylaxis regimen including combined general and epidural anesthesia, intraoperative calf bandaging, early mobilization, and postoperative intermittent pneumatic compression with additional use of elastic stockings. Duplex ultrasonography was performed routinely to diagnose deep venous thrombosis in all patients before surgery and on Postoperative Days 3 and 21. All patients with postoperative deep venous thrombosis underwent additional ultrasonography at 3-month intervals, and all patients were followed postoperatively for 6 months or more.
RESULTS: Preoperatively, we found asymptomatic deep venous thrombosis in two patients (1%); both thromboses had completely and spontaneously resolved by Postoperative Day 21. Postoperatively, no patients had a fatal or symptomatic pulmonary embolism or proximal deep venous thrombosis, but nine patients (5%) had asymptomatic distal deep venous thrombosis develop, with no preoperative associated factors. These nine patients were followed closely without anticoagulant drugs, and all thromboses had disappeared without pulmonary embolism or thrombophlebitis by 6 months.
CONCLUSIONS: The incidence of preoperative and postoperative deep venous thrombosis was low in an Asian population having elective hip surgery and a nonpharmacologic thromboprophylaxis regimen. There were no preoperative factors associated with postoperative deep venous thrombosis, and all asymptomatic deep venous thromboses resolved spontaneously without associated pulmonary embolism or thrombophlebitis. LEVEL OF EVIDENCE: Level IV, therapeutic study. See the Guidelines for Authors for a complete description of levels of evidence.

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Year:  2010        PMID: 20058109      PMCID: PMC2919892          DOI: 10.1007/s11999-009-1220-0

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  32 in total

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  7 in total

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Authors:  Kosuke Tsuda; Takashi Nishii; Takashi Sakai; Masaki Takao; Nobuo Nakamura; Nobuhiko Sugano
Journal:  J Thromb Thrombolysis       Date:  2016-04       Impact factor: 2.300

Review 2.  Transient portal vein thrombosis in liver cirrhosis.

Authors:  Xingshun Qi; Xiaozhong Guo; Eric M Yoshida; Nahum Méndez-Sánchez; Valerio De Stefano; Frank Tacke; Andrea Mancuso; Yasuhiko Sugawara; Sien-Sing Yang; Rolf Teschke; Ankur Arora; Dominique-Charles Valla
Journal:  BMC Med       Date:  2018-06-05       Impact factor: 8.775

3.  Risk of Venous Thromboembolic Events in Patients with Osteonecrosis of the Femoral Head Undergoing Primary Hip Arthroplasty.

Authors:  Pei-Hsun Sung; Yao-Hsu Yang; Hsin-Ju Chiang; John Y Chiang; Hon-Kan Yip; Mel S Lee
Journal:  J Clin Med       Date:  2019-12-06       Impact factor: 4.241

4.  Feasibility and Safety of a Novel Leg Exercise Apparatus for Venous Thromboembolism Prophylaxis after Total Joint Arthroplasty of the Lower Extremities-A Pilot Study.

Authors:  Kenta Tanaka; Yukiyo Shimizu; Hiroshi Kamada; Shizu Aikawa; Hajime Mishima; Akihiro Kanamori; Tomofumi Nishino; Masataka Sakane; Naoyuki Ochiai; Masashi Yamazaki
Journal:  Tomography       Date:  2021-11-04

5.  Association Between Simultaneous Bilateral Total Hip Arthroplasty Without Any Anticoagulant or Antiplatelet Therapy and Deep Venous Thrombosis: A Cohort Study.

Authors:  Masaki Hatano; Masaki Nakamura; Hiroyuki Ohbe; Izuru Kitajima; Kazuya Isawa; Seizo Yamamoto
Journal:  Arthroplast Today       Date:  2021-12-15

6.  Impact of anesthesia modality and mechanical venous thromboembolism prophylaxis on the incidence of symptomatic deep venous thrombosis after TKA.

Authors:  Yoshinori Ishii; Hideo Noguchi; Junko Sato; Satoshi Takayama; Yui Okada; Shin-Ichi Toyabe
Journal:  J Clin Orthop Trauma       Date:  2016-11-18

7.  Pharmacological thromboprophylaxis and epidural anaesthesia.

Authors:  Ss Harsoor; K Sudheesh
Journal:  Indian J Anaesth       Date:  2012-05
  7 in total

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