PURPOSE: Signet ring carcinoma (SRC) of the appendix consists one of the most biologically virulent cancers. We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix. CASE REPORT: A 78-year-old man was admitted due to a 5-day history of increasing colicky abdominal pain and vomiting. Clinical examination revealed a firm, tender mass in the right ileac fossa. Laparotomy confirmed a tumor mass which appeared to originate from the appendix. The affected part of the bowel was resected and a right hemicolectomy with an end-to-side ileotransverse anastomosis was performed. The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring. Moreover, a focus of SRC was detected. CONCLUSIONS: Appendiceal SRC is a rare entity, which may sometimes be confused with other pathologies providing difficulties in differential diagnosis, having an impact on therapeutic decisions and affecting prognosis.
PURPOSE: Signet ring carcinoma (SRC) of the appendix consists one of the most biologically virulent cancers. We present the case of a patient with primary SRC complicated by the development of acute inflammation of the appendix. CASE REPORT: A 78-year-old man was admitted due to a 5-day history of increasing colicky abdominal pain and vomiting. Clinical examination revealed a firm, tender mass in the right ileac fossa. Laparotomy confirmed a tumor mass which appeared to originate from the appendix. The affected part of the bowel was resected and a right hemicolectomy with an end-to-side ileotransverse anastomosis was performed. The appendix was notably thickened with an ulcerated wall containing sinus tracts, chronic inflammation, and scarring. Moreover, a focus of SRC was detected. CONCLUSIONS: Appendiceal SRC is a rare entity, which may sometimes be confused with other pathologies providing difficulties in differential diagnosis, having an impact on therapeutic decisions and affecting prognosis.
Authors: Marcia L McGory; Melinda A Maggard; Hakjung Kang; Jessica B O'Connell; Clifford Y Ko Journal: Dis Colon Rectum Date: 2005-12 Impact factor: 4.585
Authors: Srdjan P Djuranovic; Milan M Spuran; Nada V Kovacevic; Milenko B Ugljesic; Dragutin M Kecmanovic; Marjan T Micev Journal: World J Gastroenterol Date: 2006-03-28 Impact factor: 5.742
Authors: Mark E O'Donnell; Stephen A Badger; Garth C Beattie; Jim Carson; W Ian H Garstin Journal: Int J Colorectal Dis Date: 2007-04-20 Impact factor: 2.571
Authors: A Manigrasso; S Candioli; D Pironi; V La Torre; A Panarese; A M Romani; S Arcieri; D Tarroni; G Palazzini; A Filippini Journal: G Chir Date: 2007-03