Literature DB >> 20058077

The link between psychosis and aggression in persons with dementia: a systematic review.

Denis Shub1, Valdesha Ball, Asghar-Ali Ali Abbas, Aruna Gottumukkala, Mark E Kunik.   

Abstract

The purpose of this study was to systematically review the literature to determine whether aggression is linked to psychosis in persons with dementia. An electronic search using PubMed for articles in English focusing on psychosis and aggression or agitation in adults aged 65+ with dementia. Cross-sectional, longitudinal, and randomized controlled treatment studies examining the outcomes of aggression and psychosis were eligible for inclusion. Eighteen articles were selected for final analysis. Of the seven cross-sectional and two longitudinal studies directly examining the correlation of aggression and psychosis, most showed a positive association. Outcome data from the nine treatment studies was more mixed. Limited data link psychosis with aggression in persons with dementia. Prospectively designed studies looking at the temporal relationship of these variables are needed to make a stronger causal argument.

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Year:  2010        PMID: 20058077     DOI: 10.1007/s11126-009-9121-7

Source DB:  PubMed          Journal:  Psychiatr Q        ISSN: 0033-2720


  35 in total

Review 1.  The impact of the symptoms of dementia on caregivers.

Authors:  C Donaldson; N Tarrier; A Burns
Journal:  Br J Psychiatry       Date:  1997-01       Impact factor: 9.319

2.  Comparison of olanzapine and risperidone in the treatment of psychosis and associated behavioral disturbances in patients with dementia.

Authors:  Walter G Deberdt; Maurice W Dysken; Stephen A Rappaport; Peter D Feldman; Carrie A Young; Donald P Hay; Deborah L Lehman; Martin Dossenbach; Elisabeth K Degenhardt; Alan Breier
Journal:  Am J Geriatr Psychiatry       Date:  2005-08       Impact factor: 4.105

3.  Mental health correlates of aggression in nursing home residents with dementia.

Authors:  Karen Amann Talerico; Lois K Evans; Neville E Strumpf
Journal:  Gerontologist       Date:  2002-04

4.  Psychosis, depression and behavioural disturbances in Sydney nursing home residents: prevalence and predictors.

Authors:  H Brodaty; B Draper; D Saab; L F Low; V Richards; H Paton; D Lie
Journal:  Int J Geriatr Psychiatry       Date:  2001-05       Impact factor: 3.485

5.  Neuropathologic and neurochemical correlates of psychosis in primary dementia.

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Journal:  Arch Neurol       Date:  1991-06

6.  Quetiapine treatment of psychosis associated with dementia: a double-blind, randomized, placebo-controlled clinical trial.

Authors:  Pierre N Tariot; Lon Schneider; Ira R Katz; Jacobo E Mintzer; Jamie Street; Margaret Copenhaver; Celeste Williams-Hughes
Journal:  Am J Geriatr Psychiatry       Date:  2006-08-11       Impact factor: 4.105

7.  Olanzapine treatment of psychotic and behavioral symptoms in patients with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study Group.

Authors:  J S Street; W S Clark; K S Gannon; J L Cummings; F P Bymaster; R N Tamura; S J Mitan; D L Kadam; T M Sanger; P D Feldman; G D Tollefson; A Breier
Journal:  Arch Gen Psychiatry       Date:  2000-10

8.  Olanzapine (Zyprexa): increased incidence of cerebrovascular events in dementia trials.

Authors:  Eric Wooltorton
Journal:  CMAJ       Date:  2004-04-27       Impact factor: 8.262

9.  Olanzapine versus placebo in the treatment of psychosis with or without associated behavioral disturbances in patients with Alzheimer's disease.

Authors:  Peter Paul De Deyn; Manuel Martín Carrasco; Walter Deberdt; Claude Jeandel; Donald P Hay; Peter D Feldman; Carrie A Young; Deborah L Lehman; Alan Breier
Journal:  Int J Geriatr Psychiatry       Date:  2004-02       Impact factor: 3.485

10.  Psychiatric symptoms and nursing home placement of patients with Alzheimer's disease.

Authors:  C Steele; B Rovner; G A Chase; M Folstein
Journal:  Am J Psychiatry       Date:  1990-08       Impact factor: 18.112

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  3 in total

Review 1.  Understanding aggressive behaviour across the lifespan.

Authors:  J Liu; G Lewis; L Evans
Journal:  J Psychiatr Ment Health Nurs       Date:  2012-04-04       Impact factor: 2.952

2.  Systematic reviews on behavioural and psychological symptoms in the older or demented population.

Authors:  Rianne M van der Linde; Blossom Cm Stephan; George M Savva; Tom Dening; Carol Brayne
Journal:  Alzheimers Res Ther       Date:  2012-07-11       Impact factor: 6.982

3.  Antipsychotic use in dementia: the relationship between neuropsychiatric symptom profiles and adverse outcomes.

Authors:  Christoph Mueller; Christeena John; Gayan Perera; Dag Aarsland; Clive Ballard; Robert Stewart
Journal:  Eur J Epidemiol       Date:  2020-05-15       Impact factor: 8.082

  3 in total

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