Literature DB >> 20057421

Huntington's disease: tagged for clearance.

Dimitri Krainc.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 20057421     DOI： 10.1038/nm0110-32

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


× No keyword cloud information.
  8 in total

1.  Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.

Authors:  A Yamamoto; J J Lucas; R Hen
Journal:  Cell       Date:  2000-03-31       Impact factor: 41.582

2.  Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death.

Authors:  Montserrat Arrasate; Siddhartha Mitra; Erik S Schweitzer; Mark R Segal; Steven Finkbeiner
Journal:  Nature       Date:  2004-10-14       Impact factor: 49.962

Review 3.  Pathophysiology of Huntington's disease: from huntingtin functions to potential treatments.

Authors:  Emmanuel Roze; Frédéric Saudou; Jocelyne Caboche
Journal:  Curr Opin Neurol       Date:  2008-08       Impact factor: 5.710

4.  IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.

Authors:  Leslie Michels Thompson; Charity T Aiken; Linda S Kaltenbach; Namita Agrawal; Katalin Illes; Ali Khoshnan; Marta Martinez-Vincente; Montserrat Arrasate; Jacqueline Gire O'Rourke; Hasan Khashwji; Tamas Lukacsovich; Ya-Zhen Zhu; Alice L Lau; Ashish Massey; Michael R Hayden; Scott O Zeitlin; Steven Finkbeiner; Kim N Green; Frank M LaFerla; Gillian Bates; Lan Huang; Paul H Patterson; Donald C Lo; Ana Maria Cuervo; J Lawrence Marsh; Joan S Steffan
Journal:  J Cell Biol       Date:  2009-12-21       Impact factor: 10.539

Review 5.  Therapeutic application of histone deacetylase inhibitors for central nervous system disorders.

Authors:  Aleksey G Kazantsev; Leslie M Thompson
Journal:  Nat Rev Drug Discov       Date:  2008-10       Impact factor: 84.694

6.  Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.

Authors:  Brinda Ravikumar; Coralie Vacher; Zdenek Berger; Janet E Davies; Shouqing Luo; Lourdes G Oroz; Francesco Scaravilli; Douglas F Easton; Rainer Duden; Cahir J O'Kane; David C Rubinsztein
Journal:  Nat Genet       Date:  2004-05-16       Impact factor: 38.330

7.  Acetylation targets mutant huntingtin to autophagosomes for degradation.

Authors:  Hyunkyung Jeong; Florian Then; Thomas J Melia; Joseph R Mazzulli; Libin Cui; Jeffrey N Savas; Cindy Voisine; Paolo Paganetti; Naoko Tanese; Anne C Hart; Ai Yamamoto; Dimitri Krainc
Journal:  Cell       Date:  2009-04-03       Impact factor: 41.582

8.  Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice.

Authors:  Xiaofeng Gu; Erin R Greiner; Rakesh Mishra; Ravindra Kodali; Alex Osmand; Steven Finkbeiner; Joan S Steffan; Leslie Michels Thompson; Ronald Wetzel; X William Yang
Journal:  Neuron       Date:  2009-12-24       Impact factor: 17.173
  8 in total
  3 in total

1.  Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

Authors:  Stephen J McConoughey; Manuela Basso; Zoya V Niatsetskaya; Sama F Sleiman; Natalia A Smirnova; Brett C Langley; Lata Mahishi; Arthur J L Cooper; Marc A Antonyak; Rick A Cerione; Bo Li; Anatoly Starkov; Rajnish Kumar Chaturvedi; M Flint Beal; Giovanni Coppola; Daniel H Geschwind; Hoon Ryu; Li Xia; Siiri E Iismaa; Judit Pallos; Ralf Pasternack; Martin Hils; Jing Fan; Lynn A Raymond; J Lawrence Marsh; Leslie M Thompson; Rajiv R Ratan
Journal:  EMBO Mol Med       Date:  2010-09       Impact factor: 12.137

2.  Glycation potentiates neurodegeneration in models of Huntington's disease.

Authors:  Hugo Vicente Miranda; Marcos António Gomes; Joana Branco-Santos; Carlo Breda; Diana F Lázaro; Luísa Vaqueiro Lopes; Federico Herrera; Flaviano Giorgini; Tiago Fleming Outeiro
Journal:  Sci Rep       Date:  2016-11-18       Impact factor: 4.379

3.  Development of an ELISA assay for the quantification of soluble huntingtin in human blood cells.

Authors:  Luisa Massai; Lara Petricca; Letizia Magnoni; Luca Rovetini; Salman Haider; Ralph Andre; Sarah J Tabrizi; Sigurd D Süssmuth; Bernhard G Landwehrmeyer; Andrea Caricasole; Giuseppe Pollio; Simonetta Bernocco
Journal:  BMC Biochem       Date:  2013-11-25       Impact factor: 4.059
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.