Literature DB >> 20057325

Small cell ovarian carcinoma: a rare, aggressive tumor masquerading as constipation in a teenager with a fatal outcome.

Jesse Barondeau1, Matthew Rodgers, Loranee Braun, Kenneth Azarow, Melissa Forouhar, Kelly Faucette.   

Abstract

SUMMARY: A 16-year-old female presented with symptoms consistent with constipation with no constitutional symptoms. Multiple different laxatives were attempted over 4 months and were unsuccessful. This thin female developed an impressively distended, nonacute abdomen within a 2-week period. Histology demonstrated a stage IV small cell carcinoma of the ovary. Her disease initially responded to treatment, but ultimately she relapsed and failed to respond to 2 other chemotherapy combinations, which were based on limited success found in the literature. She ultimately passed away 13 months after the diagnosis, demonstrating the poor prognosis and rapid spread of this rare disease.

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Year:  2010        PMID: 20057325     DOI: 10.1097/MPH.0b013e3181bdbc8d

Source DB:  PubMed          Journal:  J Pediatr Hematol Oncol        ISSN: 1077-4114            Impact factor:   1.289


  6 in total

1.  Small Cell Ovarian Carcinomas - Characterisation of Two Rare Tumor Entities.

Authors:  K Münstedt; R Estel; T Dreyer; A Kurata; A Benz
Journal:  Geburtshilfe Frauenheilkd       Date:  2013-07       Impact factor: 2.915

2.  A case of small cell carcinoma of the ovary hypercalcemic variant in a teenager.

Authors:  Arvind Bakhru; J Rebecca Liu; Amir Lagstein
Journal:  Gynecol Oncol Case Rep       Date:  2012-09-19

3.  Small cell ovarian carcinoma: genomic stability and responsiveness to therapeutics.

Authors:  Lisa F Gamwell; Karen Gambaro; Maria Merziotis; Colleen Crane; Suzanna L Arcand; Valerie Bourada; Christopher Davis; Jeremy A Squire; David G Huntsman; Patricia N Tonin; Barbara C Vanderhyden
Journal:  Orphanet J Rare Dis       Date:  2013-02-21       Impact factor: 4.123

4.  Molecular Characterization of a Patient's Small Cell Carcinoma of the Ovary of the Hypercalcemic Type.

Authors:  Bret Stephens; Stephen P Anthony; Haiyong Han; Jeffery Kiefer; Galen Hostetter; Michael Barrett; Daniel D Von Hoff
Journal:  J Cancer       Date:  2012-01-26       Impact factor: 4.207

5.  Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT) beyond SMARCA4 Mutations: A Comprehensive Genomic Analysis.

Authors:  Aurélie Auguste; Félix Blanc-Durand; Marc Deloger; Audrey Le Formal; Rohan Bareja; David C Wilkes; Catherine Richon; Béatrice Brunn; Olivier Caron; Mojgan Devouassoux-Shisheboran; Sébastien Gouy; Philippe Morice; Enrica Bentivegna; Andrea Sboner; Olivier Elemento; Mark A Rubin; Patricia Pautier; Catherine Genestie; Joanna Cyrta; Alexandra Leary
Journal:  Cells       Date:  2020-06-19       Impact factor: 6.600

6.  In vitro and in vivo therapeutic approach for a small cell carcinoma of the ovary hypercalcaemic type using a SCCOHT-1 cellular model.

Authors:  Anna Otte; Finn Rauprich; Peter Hillemanns; Tjoung-Won Park-Simon; Juliane von der Ohe; Ralf Hass
Journal:  Orphanet J Rare Dis       Date:  2014-08-08       Impact factor: 4.123

  6 in total

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