Literature DB >> 2005631

Biological consequences of gene regulation after ionizing radiation exposure.

R R Weichselbaum1, D E Hallahan, V Sukhatme, A Dritschilo, M L Sherman, D W Kufe.   

Abstract

Ionizing radiation is a ubiquitous environmental mutagen and carcinogen widely used in cancer therapy. However, little is known about the induction of cellular signaling events and specific gene expression after radiation exposure. We review the accumulating evidence that ionizing radiation induces signal transduction pathways involving activation of protein kinase C and a program of genetic events that may contribute to the biological effects of x rays.

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Year:  1991        PMID： 2005631     DOI： 10.1093/jnci/83.7.480

Source DB:  PubMed          Journal:  J Natl Cancer Inst        ISSN： 0027-8874            Impact factor:   13.506


  18 in total

Review 1.  Early and late effects of radiation treatment for prevention of coronary restenosis: a critical appraisal.

Authors:  O F Bertrand; S Lehnert; R Mongrain; M G Bourassa
Journal:  Heart       Date:  1999-12       Impact factor: 5.994

2.  Transcription and activity of antioxidant enzymes after ionizing irradiation in radiation-resistant and radiation-sensitive mice.

Authors:  R Hardmeier; H Hoeger; S Fang-Kircher; A Khoschsorur; G Lubec
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-08       Impact factor: 11.205

3.  Ionizing radiation stimulates octamer factor DNA binding activity in human carcinoma cells.

Authors:  R L Meighan-Mantha; A T Riegel; S Suy; V Harris; F H Wang; C Lozano; T L Whiteside; U Kasid
Journal:  Mol Cell Biochem       Date:  1999-09       Impact factor: 3.396

Review 4.  Regulation of the cell cycle following DNA damage in normal and Ataxia telangiectasia cells.

Authors:  H D Lohrer
Journal:  Experientia       Date:  1996-04-15

Review 5.  The biology of radioresistance: similarities, differences and interactions with drug resistance.

Authors:  S N Powell; E H Abraham
Journal:  Cytotechnology       Date:  1993       Impact factor: 2.058

6.  Delayed chromosomal instability induced by DNA damage.

Authors:  B A Marder; W F Morgan
Journal:  Mol Cell Biol       Date:  1993-11       Impact factor: 4.272

7.  Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

Authors:  Q Zhan; F Carrier; A J Fornace
Journal:  Mol Cell Biol       Date:  1993-07       Impact factor: 4.272

8.  A gene trap approach to isolate mammalian genes involved in the cellular response to genotoxic stress.

Authors:  P Menichini; S Viaggi; E Gallerani; G Fronza; L Ottaggio; A Comes; J W Ellwart; A Abbondandolo
Journal:  Nucleic Acids Res       Date:  1997-12-01       Impact factor: 16.971

9.  Activation of IL-6 production by UV irradiation of blood mononuclear cells from patients with systemic lupus erythematosus.

Authors:  B K Pelton; W Hylton; A M Denman
Journal:  Clin Exp Immunol       Date:  1992-08       Impact factor: 4.330

10.  Radiation Genes: a database devoted to microarrays screenings revealing transcriptome alterations induced by ionizing radiation in mammalian cells.

Authors:  Francesco Chiani; Camilla Iannone; Rodolfo Negri; Daniele Paoletti; Mattia D'Antonio; Paolo D'onorio De Meo; Tiziana Castrignanò
Journal:  Database (Oxford)       Date:  2009-07-28       Impact factor: 3.451
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