| Literature DB >> 20056052 |
Ewan Bigsby1, Arindam Chaudhuri, Alastair Whiteway.
Abstract
A 56-year-old man developed mid-gut bowel ischaemia following an elective aortobiprofunda bypass for short-distance claudication. The bowel was resected and he was commenced on lifelong total parenteral nutrition. He was found to have developed heparin-induced thrombocytopenia and thrombosis, confirmed by high levels of heparin-platelet factor 4-antibody on enzyme-linked immunosorbent assay (ELISA). He subsequently had foregut ischaemia with a second bout of thrombocytopenia despite not being on heparin. The case describes the first report of bowel ischaemia as a consequence of heparin-induced thrombocytopenia causing sequential superior mesenteric and coeliac arterial thrombosis in this scenario and highlights the importance of the awareness of the association of these pathological entities and subsequent management.Entities:
Mesh:
Substances:
Year: 2010 PMID: 20056052 PMCID: PMC5696817 DOI: 10.1308/147870810X476629
Source DB: PubMed Journal: Ann R Coll Surg Engl ISSN: 0035-8843 Impact factor: 1.891