Literature DB >> 20056052

Mesenteric and coeliac occlusions following heparin-induced thrombocytopenia after aortobiprofunda bypass surgery.

Ewan Bigsby1, Arindam Chaudhuri, Alastair Whiteway.   

Abstract

A 56-year-old man developed mid-gut bowel ischaemia following an elective aortobiprofunda bypass for short-distance claudication. The bowel was resected and he was commenced on lifelong total parenteral nutrition. He was found to have developed heparin-induced thrombocytopenia and thrombosis, confirmed by high levels of heparin-platelet factor 4-antibody on enzyme-linked immunosorbent assay (ELISA). He subsequently had foregut ischaemia with a second bout of thrombocytopenia despite not being on heparin. The case describes the first report of bowel ischaemia as a consequence of heparin-induced thrombocytopenia causing sequential superior mesenteric and coeliac arterial thrombosis in this scenario and highlights the importance of the awareness of the association of these pathological entities and subsequent management.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20056052      PMCID: PMC5696817          DOI: 10.1308/147870810X476629

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  5 in total

Review 1.  Heparin-induced thrombocytopenia: a clinicopathologic syndrome.

Authors:  T E Warkentin
Journal:  Thromb Haemost       Date:  1999-08       Impact factor: 5.249

2.  The management of heparin-induced thrombocytopenia.

Authors:  David Keeling; Simon Davidson; Henry Watson
Journal:  Br J Haematol       Date:  2006-05       Impact factor: 6.998

3.  Heparin-induced vascular occlusion in vasculosurgical patients. An evaluation of the disease in 13 cases.

Authors:  T Buerger; J Tautenhahn; F Meyer; H Lippert
Journal:  J Cardiovasc Surg (Torino)       Date:  1999-04       Impact factor: 1.888

Review 4.  When heparins promote thrombosis: review of heparin-induced thrombocytopenia.

Authors:  Ik-Kyung Jang; Marcie J Hursting
Journal:  Circulation       Date:  2005-05-24       Impact factor: 29.690

5.  Quantitative interpretation of optical density measurements using PF4-dependent enzyme-immunoassays.

Authors:  T E Warkentin; J I Sheppard; J C Moore; C S Sigouin; J G Kelton
Journal:  J Thromb Haemost       Date:  2008-05-17       Impact factor: 5.824

  5 in total
  1 in total

Review 1.  Anticoagulants for the prevention and treatment of catheter-related thrombosis in adults and children on parenteral nutrition: a systematic review and critical appraisal.

Authors:  Stefano Barco; Jasper J Atema; Michiel Coppens; Mireille J Serlie; Saskia Middeldorp
Journal:  Blood Transfus       Date:  2016-07-21       Impact factor: 3.443

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.