Literature DB >> 20055844

Composite haemangioendothelioma with lymph-node metastasis: an unusual presentation at an uncommon site.

I E Aydingöz1, C Demirkesen, Z A Serdar, A T Mansur, S Yaşar, C Aslan.   

Abstract

A 48-year-old woman presented with red papules on the thigh. Histopathological examination indicated pyogenic granuloma, and the patient was treated with total excision in 2003 and electrocauterization in 2005. Three months later, upon recurrence of the lesions, a diagnosis of composite haemangioendothelioma (CHE) was made. The patient was treated by total excision and lymph-node dissection, which revealed inguinal lymph-node metastasis. Despite the surgery, a further local recurrence occurred, subsequently treated by wide excision en bloc, with adjuvant radiotherapy and chemotherapy. Although CHE is defined as a vascular tumour with low-grade malignancy, the local recurrences and lymph-node metastases resulted in treatment difficulties in this case. Unlike earlier cases, the tumour in our patient presented as localized numerous small papulonodules, and lymph-node metastasis was detected within a relatively short time. Dermatologists and pathologists should be aware of this rare condition and include it in the differential diagnosis of vascular lesions.

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Year:  2009        PMID: 20055844     DOI: 10.1111/j.1365-2230.2009.03529.x

Source DB:  PubMed          Journal:  Clin Exp Dermatol        ISSN: 0307-6938            Impact factor:   3.470


  7 in total

1.  Composite Hemangioendothelioma of the Submandibular Region.

Authors:  Sarah Lam Shang Leen; Peter M Clarke; John Chapman; Cyril Fisher; Khin Thway
Journal:  Head Neck Pathol       Date:  2015-02-10

2.  Composite hemangioendothelioma with neuroendocrine marker expression: an aggressive variant.

Authors:  Kyle D Perry; Alyaa Al-Lbraheemi; Brian P Rubin; Jin Jen; Hongzheng Ren; Jin Sung Jang; Asha Nair; Jaime Davila; Stefan Pambuccian; Andrew Horvai; William Sukov; Henry D Tazelaar; Andrew L Folpe
Journal:  Mod Pathol       Date:  2017-07-21       Impact factor: 7.842

3.  Primary Alopecia Neoplastica: A Novel Case Report and Literature Review.

Authors:  Kelly E Flanagan; Laura J Burns; James T Pathoulas; Chloe J Walker; Isabel Pupo Wiss; Kristine M Cornejo; Maryanne M Senna
Journal:  Skin Appendage Disord       Date:  2021-06-16

4.  Whole Exome Sequencing Identifies Somatic Variants in an Oral Composite Hemangioendothelioma Characterized by YAP1-MAML2 Fusion.

Authors:  Ioannis G Koutlas; William S Oetting; Gregory M Burns; Rajaram Gopalakrishnan; Cristina R Antonescu
Journal:  Head Neck Pathol       Date:  2021-11-17

Review 5.  Composite hemangioendothelioma arising from the kidney: case report with review of the literature.

Authors:  Jin Zhang; Bo Wu; Gui-Qian Zhou; Ru-Song Zhang; Xue Wei; Bo Yu; Zhen-Feng Lu; Heng-Hui Ma; Qun-Li Shi; Xiao-Jun Zhou
Journal:  Int J Clin Exp Pathol       Date:  2013-08-15

6.  Composite hemangioendothelioma of the spleen with multiple metastases: CT findings and review of the literature.

Authors:  Wei Wei Li; Pan Liang; Hui Ping Zhao; Yan Xing Zhang; Yi Yang Liu; Jian Bo Gao
Journal:  Medicine (Baltimore)       Date:  2021-05-28       Impact factor: 1.817

Review 7.  Cutaneous composite hemangioendothelioma: case report and review of published reports.

Authors:  Zorica Stojsic; Dimitrije Brasanac; Martina Stojanovic; Mladen Boricic
Journal:  Ann Saudi Med       Date:  2014 Mar-Apr       Impact factor: 1.526

  7 in total

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