Literature DB >> 20055169

[Recent advances in the applications of ultrasonic microbubbles as gene or drug vectors].

Yuan-Yuan Shen1, Zhong-Gao Gao, Natalya Rapoport.   

Abstract

With the research and application of the new ultrasound microbubble contrast agents, ultrasonic microbubbles can not only help to image, but they can also be used as genes or drug carriers. The microbubbles as genes or drug carriers can pass across the endothelial cell barrier and release genes and drug under the action of ultrasound field, which achieve target treatment effect. Based on the relevant materials, the bioeffects, early successes with gene and drug delivery, and potential clinical applications are reviewed.

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Year:  2009        PMID: 20055169

Source DB:  PubMed          Journal:  Yao Xue Xue Bao        ISSN: 0513-4870


  3 in total

1.  Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery and nuclear trafficking.

Authors:  Praveena Mohan; Natalya Rapoport
Journal:  Mol Pharm       Date:  2010-10-27       Impact factor: 4.939

Review 2.  Advances in ultrasound-targeted microbubble-mediated gene therapy for liver fibrosis.

Authors:  Cuiyuan Huang; Hong Zhang; Ruidan Bai
Journal:  Acta Pharm Sin B       Date:  2017-03-15       Impact factor: 11.413

3.  PLGA nanoparticles delivering CPT-11 combined with focused ultrasound inhibit platinum resistant ovarian cancer.

Authors:  Xiaogang Zhu; Siqi Yan; Fang Xiao; Min Xue
Journal:  Transl Cancer Res       Date:  2021-04       Impact factor: 1.241

  3 in total

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