Literature DB >> 20053563

Identification of potential and selective collagenase, gelatinase inhibitors from Crataegus pinnatifida.

Hyung-In Moon1, Tae-im Kim, Hyun-Soo Cho, Eung Kweon Kim.   

Abstract

Four oligomeric procyanidins were isolated from the MeOH extracts of the leaves of Crataegus pinnatifida (Rosaceae). Investigation of collagenase and gelatinase inhibitory natural components afforded four oligomeric procyanidins. Of these, 2 and 3 exhibited collagenase inhibitory activity (IC(50)) at a concentration of less than 1 microM, and 3 showed gelatinases A and B inhibitory activity (IC(50)) at 0.4 and 2.3 microM, respectively. Copyright (c) 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID: 20053563     DOI: 10.1016/j.bmcl.2009.12.059

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN: 0960-894X            Impact factor:   2.823


  2 in total

1.  Inhibition of Collagenase by Mycosporine-like Amino Acids from Marine Sources.

Authors:  Anja Hartmann; Johanna Gostner; Julian E Fuchs; Eliza Chaita; Nektarios Aligiannis; Leandros Skaltsounis; Markus Ganzera
Journal:  Planta Med       Date:  2015-06-03       Impact factor: 3.352

Review 2.  Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits.

Authors:  Tunde Jurikova; Jiri Sochor; Otakar Rop; Jiri Mlcek; Stefan Balla; Ladislav Szekeres; Vojtech Adam; Rene Kizek
Journal:  Molecules       Date:  2012-12-06       Impact factor: 4.411

  2 in total

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