PURPOSE: Misuse of high-dose buprenorphine (HDB), mainly by injection, is responsible of frequent infectious adverse events. METHODS: This is a retrospective study of infectious complications occurring in patients using HDB by injection. Forty-two cases were identified (29 men and ten women) and the data were collected between March 1999 and December 2008. RESULTS: The infectious complications included cutaneous infections (27 cases), endocarditis (nine cases), osteoarticular infections (four spondylodiscitis and one sacroiliitis), and a vascular embolism with decrease in visual acuity. CONCLUSION: The results of HDB maintenance treatment must be improved, both from the point of view of substitution and to limit its misuse by intravenous route injection. Health professionals have to play an important role in drug addict patients' education and supervision, to prevent buprenorphine injection and related infectious complications. 2009 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
PURPOSE: Misuse of high-dose buprenorphine (HDB), mainly by injection, is responsible of frequent infectious adverse events. METHODS: This is a retrospective study of infectious complications occurring in patients using HDB by injection. Forty-two cases were identified (29 men and ten women) and the data were collected between March 1999 and December 2008. RESULTS: The infectious complications included cutaneous infections (27 cases), endocarditis (nine cases), osteoarticular infections (four spondylodiscitis and one sacroiliitis), and a vascular embolism with decrease in visual acuity. CONCLUSION: The results of HDB maintenance treatment must be improved, both from the point of view of substitution and to limit its misuse by intravenous route injection. Health professionals have to play an important role in drug addictpatients' education and supervision, to prevent buprenorphine injection and related infectious complications. 2009 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
Authors: Régis Bouquié; Laura Wainstein; Paul Pilet; Jean-Marie Mussini; Guillaume Deslandes; Johann Clouet; Eric Dailly; Pascale Jolliet; Caroline Victorri-Vigneau Journal: PLoS One Date: 2014-12-04 Impact factor: 3.240
Authors: Nobila Valentin Yameogo; Kongnimisson Apoline Sondo; Aime Arsene Yameogo; Larissa Justine Kagambega; D Germain Mandi; K Jonas Kologo; Georges R C Millogo; B Jean Yves Toguyeni; Andre K Samadoulougou; N Jean-Paul Kabore; Patrice Zabsonre Journal: Cardiovasc J Afr Date: 2013-06 Impact factor: 1.167