Literature DB >> 20053475

Genetic association of the neuropilin-1 gene with type 1 diabetes in children: Neuropilin-1 expression in pancreatic islets.

Noaman M Hasan1, Mindy A Kendrick, Noah R Druckenbrod, Michael K Huelsmeyer, Thomas F Warner, Michael J MacDonald.   

Abstract

Minor alleles of two SNPs in intron 9 of the NRP1 gene, which encodes neuropilin-1, were found to be associated with type 1 diabetes (T1D) in children. Neuropilin-1 peptides were confined to islets in human pancreas. This suggests neuropilins-1 could influence the development of some cases of T1D in children.

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Year:  2010        PMID： 20053475     DOI： 10.1016/j.diabres.2009.12.016

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  13 in total

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