Literature DB >> 20053440

Cu2+-labeled, SPION loaded porous silica nanoparticles for cell labeling and multifunctional imaging probes.

Daksha Patel1, Arnold Kell, Benoit Simard, Jixian Deng, Bo Xiang, Hung-Yu Lin, Marco Gruwel, Ganghong Tian.   

Abstract

We have developed an ion-sensing nanoparticle that is comprised of a superparamagnetic iron oxide (SPIO) core encapsulated with a porous silica shell. The latter can be readily anchored with ligands capable of coordinating with positron-emitting metal. Evidently, this nanoparticle has a great potential for use in cell tracking with magnetic resonance (MR) imaging and positron emission tomography (PET). Herein we report the synthesis, surface functionalization and characterization of the magnetic nanoparticle-based probes and evaluate their cell-labeling efficacy, cytotoxicity and relaxivity in comparison to one of the most commonly utilized MRI contrast agents, Feridex. 2009. Published by Elsevier Ltd. All rights reserved.

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Year:  2010        PMID： 20053440     DOI： 10.1016/j.biomaterials.2009.12.025

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  18 in total

1.  Nonporous Silica Nanoparticles for Nanomedicine Application.

Authors:  Li Tang; Jianjun Cheng
Journal:  Nano Today       Date:  2013-06       Impact factor: 20.722

Review 2.  Genetic engineered molecular imaging probes for applications in cell therapy: emphasis on MRI approach.

Authors:  In K Cho; Silun Wang; Hui Mao; Anthony Ws Chan
Journal:  Am J Nucl Med Mol Imaging       Date:  2016-09-22

3.  Peptide-conjugated polymeric micellar nanoparticles for Dual SPECT and optical imaging of EphB4 receptors in prostate cancer xenografts.

Authors:  Rui Zhang; Chiyi Xiong; Miao Huang; Min Zhou; Qian Huang; Xiaoxia Wen; Dong Liang; Chun Li
Journal:  Biomaterials       Date:  2011-05-25       Impact factor: 12.479

4.  Radiolabeled polyoxometalate clusters: Kidney dysfunction evaluation and tumor diagnosis by positron emission tomography imaging.

Authors:  Dalong Ni; Dawei Jiang; Hyung-Jun Im; Hector F Valdovinos; Bo Yu; Shreya Goel; Todd E Barnhart; Peng Huang; Weibo Cai
Journal:  Biomaterials       Date:  2018-04-12       Impact factor: 12.479

5.  Multimodality and nanoparticles in medical imaging.

Authors:  Wen-Yen Huang; Jason J Davis
Journal:  Dalton Trans       Date:  2011-03-14       Impact factor: 4.390

6.  Multifunctional nanoscale strategies for enhancing and monitoring blood vessel regeneration.

Authors:  Eunna Chung; Laura M Ricles; Ryan S Stowers; Seung Yun Nam; Stanislav Y Emelianov; Laura J Suggs
Journal:  Nano Today       Date:  2012-11-17       Impact factor: 20.722

7.  Functionalized NaA nanozeolites labeled with 224,225Ra for targeted alpha therapy.

Authors:  Agata Piotrowska; Edyta Leszczuk; Frank Bruchertseifer; Alfred Morgenstern; Aleksander Bilewicz
Journal:  J Nanopart Res       Date:  2013-10-31       Impact factor: 2.253

Review 8.  Multimodality Imaging Agents with PET as the Fundamental Pillar.

Authors:  Dalong Ni; Emily B Ehlerding; Weibo Cai
Journal:  Angew Chem Int Ed Engl       Date:  2018-12-11       Impact factor: 15.336

Review 9.  Functionalized nanostructures with application in regenerative medicine.

Authors:  Macarena Perán; María A García; Elena López-Ruiz; Milán Bustamante; Gema Jiménez; Roberto Madeddu; Juan A Marchal
Journal:  Int J Mol Sci       Date:  2012-03-22       Impact factor: 6.208

10.  Organization of research team for nano-associated safety assessment in effort to study nanotoxicology of zinc oxide and silica nanoparticles.

Authors:  Yu-Ri Kim; Sung Ha Park; Jong-Kwon Lee; Jayoung Jeong; Ja Hei Kim; Eun-Ho Meang; Tae Hyun Yoon; Seok Tae Lim; Jae-Min Oh; Seong Soo A An; Meyoung-Kon Kim
Journal:  Int J Nanomedicine       Date:  2014-12-15
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