Literature DB >> 20053289

Benign ancient schwannoma of the abdominal wall: an unwanted birthday present.

Ravi K Bhatia1, Ayan Banerjea, Manisha Ram, Bryony E Lovett.   

Abstract

BACKGROUND: There has been a recent growth in the use of whole body Computerised Tomography (CT) scans in the private sector as a screening test for asymptomatic disease. This is despite scant evidence to show any positive effect on morbidity or mortality. There has been concern raised over the possible harms of the test in terms of radiation exposure as well as the risk and anxiety of further investigation and treatment for the large numbers of benign lesions identified. CASE
PRESENTATION: A healthy 64 year old lady received a privately funded whole body CT scan for her birthday which revealed an incidental mass in the right iliac fossa. This was investigated with further imaging and colonoscopy and as confident diagnosis could not be made, eventually excised. Histology demonstrated this to be a benign ancient schwannoma and we believe this to be the first reported case of an abdominal wall schwannoma in the English literature
CONCLUSIONS: Ancient schwannomas are rare tumours of the peripheral nerve sheaths more usually found in the head, neck and flexor surfaces of extremities. They are a subtype of classical schwannomas with a predominance of degenerative changes. Our case highlights the pitfalls of such screening tests in demonstrating benign disease and subjecting patients to what turns out to be unnecessary invasive investigation and treatment. It provides evidence as to the consequences of the large number of false positive results that are created by blind CT scanning of asymptomatic patients i.e. its tendency to detect pseudodiesease rather than affect survival rates. Should the number of scans increase there may be an unnecessary burden on NHS resources due to the large numbers of benign lesions picked up, that are then referred for further investigation.

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Year:  2010        PMID: 20053289      PMCID: PMC2820463          DOI: 10.1186/1471-2482-10-1

Source DB:  PubMed          Journal:  BMC Surg        ISSN: 1471-2482            Impact factor:   2.102


  44 in total

1.  Self-referred whole-body CT imaging: current implications for health care consumers.

Authors:  Judy Illes; Ellen Fan; Barbara A Koenig; Thomas A Raffin; Dylan Kann; Scott W Atlas
Journal:  Radiology       Date:  2003-08       Impact factor: 11.105

2.  Whole-body CT screening: edging toward commerce.

Authors:  Lee F Rogers
Journal:  AJR Am J Roentgenol       Date:  2002-10       Impact factor: 3.959

3.  Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society.

Authors:  Heber MacMahon; John H M Austin; Gordon Gamsu; Christian J Herold; James R Jett; David P Naidich; Edward F Patz; Stephen J Swensen
Journal:  Radiology       Date:  2005-11       Impact factor: 11.105

4.  Callback and follow-up guidelines for whole-body CT screening.

Authors:  Ferris M Hall; Giovanna Casola; Claude B Sirlin; Claudia D Furtado; Diego A Aguirre; Michele A Brown
Journal:  Radiology       Date:  2006-11       Impact factor: 11.105

5.  Retroperitoneal ancient schwannoma: review of clinico-radiological features.

Authors:  T K Loke; N W Yuen; K K Lo; J Lo; J C Chan
Journal:  Australas Radiol       Date:  1998-05

6.  Whole-body CT screening: spectrum of findings and recommendations in 1192 patients.

Authors:  Claudia D Furtado; Diego A Aguirre; Claude B Sirlin; David Dang; Stephan K Stamato; Patrick Lee; Farhad Sani; Michelle A Brown; David L Levin; Giovanna Casola
Journal:  Radiology       Date:  2005-09-16       Impact factor: 11.105

7.  Cytohistologic correlations in schwannomas (neurilemmomas), including "ancient," cellular, and epithelioid variants.

Authors:  Jerzy Klijanienko; Jean-Michel Caillaud; Réal Lagacé
Journal:  Diagn Cytopathol       Date:  2006-08       Impact factor: 1.582

8.  Degenerative ("ancient") changes in benign cutaneous schwannoma. A light microscopic, histochemical and immunohistochemical study.

Authors:  Z B Argenyi; K Balogh; A A Abraham
Journal:  J Cutan Pathol       Date:  1993-04       Impact factor: 1.587

Review 9.  The pathology and treatment of peripheral nerve tumors and tumor-like conditions.

Authors:  J M Woodruff
Journal:  CA Cancer J Clin       Date:  1993 Sep-Oct       Impact factor: 508.702

10.  Ancient schwannoma of the female pelvis.

Authors:  Mayumi Takeuchi; Kenji Matsuzaki; Hiromu Nishitani; Hisanori Uehara
Journal:  Abdom Imaging       Date:  2008 Mar-Apr
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  6 in total

1.  Imaging observations of a schwannoma of low malignant potential in the anterior abdominal wall: A case report.

Authors:  Yongkang Liu; Xiao Chen; Tianyao Wang; Zhongqiu Wang
Journal:  Oncol Lett       Date:  2014-07-02       Impact factor: 2.967

2.  Symptomatic schwannoma of the abdominal wall: A case report and review of the literature.

Authors:  Ruben Balzarotti; Fabio Rondelli; Jessica Barizzi; Roberto Cartolari
Journal:  Oncol Lett       Date:  2015-01-12       Impact factor: 2.967

3.  Ancient Schwannoma of the Cauda Equina: Our Experience and Review of the Literature.

Authors:  Venceslao Wierzbicki; Alessandro Pesce; Luigi Marrocco; Emanuele Piccione; Alessandro Frati; Riccardo Caruso
Journal:  Case Rep Surg       Date:  2016-12-22

4.  External Oblique Muscle Schwannoma: A Rare Anatomical Presentation.

Authors:  Daniel Paramythiotis; Diamantoula Pagkou; Moysis Moysidis; Niki Mantha; Angeliki Cheva; Antonios Michalopoulos
Journal:  Case Rep Surg       Date:  2019-09-03

5.  Abdominal wall schwannoma: case report and review of the literature.

Authors:  A Mishra; M Hamadto; M Azzabi; M Elfagieh
Journal:  Case Rep Radiol       Date:  2013-06-09

6.  Abdominal wall schwannoma: a case report.

Authors:  Mohamed Tarchouli; Mohamed Essarghini; Ouadie Qamouss; Abdennasser El Kharras; Ahmed Bounaim
Journal:  Gastroenterol Hepatol Bed Bench       Date:  2020
  6 in total

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