Literature DB >> 20051747

Calcification of the transverse ligament of the atlas in chondrocalcinosis.

Susana Roverano1, Alberto C Ortiz, Federico Ceccato, Sergio O Paira.   

Abstract

OBJECTIVE: This study seek to establish the prevalence of calcification of the transverse ligament of the atlas (TLA) and of crowned dens syndrome (CDS) in patients with articular chondrocalcinosis. It also seeks to assess the main computed tomography appearances of these calcifications. PATIENTS AND METHODS: Twenty-eight patients with articular chondrocalcinosis were prospectively evaluated for evidence of calcifications of the transverse ligament of the atlas. A group of patients with gout, fibromyalgia, and osteoarthritis were used as control.
RESULTS: Twenty-eight patients with articular chondrocalcinosis were prospectively evaluated for evidence of calcifications of the transverse ligament of the atlas. Twenty of the patients (71%) showed this calcification by computed tomography, disclosing 3 patterns of calcification: curvilinear in shape, thick, and forming a double band and mottled. Calcifications were not found in the controls (P < 0.0001). Nine patients were symptomatic (crowned dens syndrome). Patients with chondrocalcinosis and calcification of the transverse ligament of the atlas were older than the rest of the patients. Unlike the patient group, the majority of the patients in the control group were male (P = 0.02).
CONCLUSION: The presence of calcifications of the transverse ligament of the atlas in patients with chondrocalcinosis occurs more frequently than that reported earlier. The CT scan is the most sensitive method to detect it. Taking into account that calcifications of TLA may manifest as CDS in a high percentage of these patients, such possibility should be considered in all patients with neck pain, stiffness, fever, and inflammatory response so as to avoid invasive diagnostic methods and more aggressive treatments than the use of nonsteroidal anti-inflammatory drugs.

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Year:  2010        PMID: 20051747     DOI: 10.1097/RHU.0b013e3181c9484f

Source DB:  PubMed          Journal:  J Clin Rheumatol        ISSN: 1076-1608            Impact factor:   3.517


  7 in total

1.  Crowned dens syndrome.

Authors:  Akira Kuriyama
Journal:  CMAJ       Date:  2013-08-26       Impact factor: 8.262

Review 2.  A critical review of the available evidence on the diagnosis and clinical features of CPPD: do we really need imaging?

Authors:  Georgios Filippou; Emilio Filippucci; Peter Mandl; Abhishek Abhishek
Journal:  Clin Rheumatol       Date:  2020-11-24       Impact factor: 2.980

3.  Crowned Dens Syndrome: A Rare Complication of Calcium Pyrophosphate Crystal Deposition Disease.

Authors:  Thales Nogueira Gomes; Mariana Camelo Pereira; Alana Pinheiro Alves; Marcos Madeiro
Journal:  Cureus       Date:  2022-06-02

Review 4.  Crowned dens syndrome: a rare cause of acute neck pain.

Authors:  Mitchell Uh; Catharine Dewar; David Spouge; Kenneth Blocka
Journal:  Clin Rheumatol       Date:  2013-02-08       Impact factor: 2.980

5.  Upper Cervical Compression Myelopathy Caused by the Retro-Odontoid Pseudotumor With Degenerative Osteoarthritis and Calcium Pyrophosphate Dihydrate Disease: A Case Report and Literature Review.

Authors:  Takashi Yurube; Tetsuhiro Iguchi; Keisuke Kinoshita; Takashi Sadamitsu; Kenichiro Kakutani
Journal:  Neurospine       Date:  2021-12-31

6.  [Ossification of the Transverse Ligament of the Atlas on CT: Frequency and Associated Findings].

Authors:  Sukwoo Son; Jeong Ah Ryu; Tae Yeob Kim; Sungjun Kim; Seunghun Lee
Journal:  Taehan Yongsang Uihakhoe Chi       Date:  2020-05-29

7.  Crowned Dens Syndrome as a cause of acute neck pain: a Case Report and Review of the Literature.

Authors:  Ali Abdul-Rahman Younis
Journal:  Mediterr J Rheumatol       Date:  2017-06-27
  7 in total

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