Literature DB >> 20051638

The bioethics of stem cell research and therapy.

Insoo Hyun1.   

Abstract

Discussion of the bioethics of human stem cell research has transitioned from controversies over the source of human embryonic stem cells to concerns about the ethical use of stem cells in basic and clinical research. Key areas in this evolving ethical discourse include the derivation and use of other human embryonic stem cell-like stem cells that have the capacity to differentiate into all types of human tissue and the use of all types of stem cells in clinical research. Each of these issues is discussed as I summarize the past, present, and future bioethical issues in stem cell research.

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Year:  2010        PMID: 20051638      PMCID: PMC2798696          DOI: 10.1172/JCI40435

Source DB:  PubMed          Journal:  J Clin Invest        ISSN: 0021-9738            Impact factor:   14.808


  24 in total

1.  Cdx2 is essential for axial elongation in mouse development.

Authors:  Kallayanee Chawengsaksophak; Wim de Graaff; Janet Rossant; Jacqueline Deschamps; Felix Beck
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-10       Impact factor: 11.205

2.  Embryonic and extraembryonic stem cell lines derived from single mouse blastomeres.

Authors:  Young Chung; Irina Klimanskaya; Sandy Becker; Joel Marh; Shi-Jiang Lu; Julie Johnson; Lorraine Meisner; Robert Lanza
Journal:  Nature       Date:  2005-10-16       Impact factor: 49.962

3.  Altered nuclear transfer as a morally acceptable means for the procurement of human embryonic stem cells.

Authors:  William B Hurlbut
Journal:  Perspect Biol Med       Date:  2005       Impact factor: 1.416

4.  Fair payment or undue inducement?

Authors:  Insoo Hyun
Journal:  Nature       Date:  2006-08-10       Impact factor: 49.962

5.  Human research cloning, embryos, and embryo-like artifacts.

Authors:  Insoo Hyun; Kyu Won Jung
Journal:  Hastings Cent Rep       Date:  2006 Sep-Oct       Impact factor: 2.683

6.  Research sharing, ethics and public benefit.

Authors:  Patrick L Taylor
Journal:  Nat Biotechnol       Date:  2007-04       Impact factor: 54.908

7.  Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.

Authors:  Kazutoshi Takahashi; Shinya Yamanaka
Journal:  Cell       Date:  2006-08-10       Impact factor: 41.582

8.  Generation of nuclear transfer-derived pluripotent ES cells from cloned Cdx2-deficient blastocysts.

Authors:  Alexander Meissner; Rudolf Jaenisch
Journal:  Nature       Date:  2005-10-16       Impact factor: 49.962

9.  Medical innovation versus stem cell tourism.

Authors:  Olle Lindvall; Insoo Hyun
Journal:  Science       Date:  2009-06-26       Impact factor: 47.728

10.  Generation of a human embryonic stem cell line encoding the cystic fibrosis mutation deltaF508, using preimplantation genetic diagnosis.

Authors:  Susan J Pickering; Stephen L Minger; Minal Patel; Hannah Taylor; Cheryl Black; Chris J Burns; Antigoni Ekonomou; Peter R Braude
Journal:  Reprod Biomed Online       Date:  2005-03       Impact factor: 3.828

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  46 in total

1.  Human amniotic fluid stem cell preconditioning improves their regenerative potential.

Authors:  Cinzia Rota; Barbara Imberti; Michela Pozzobon; Martina Piccoli; Paolo De Coppi; Anthony Atala; Elena Gagliardini; Christodoulos Xinaris; Valentina Benedetti; Aline S C Fabricio; Elisa Squarcina; Mauro Abbate; Ariela Benigni; Giuseppe Remuzzi; Marina Morigi
Journal:  Stem Cells Dev       Date:  2011-12-23       Impact factor: 3.272

2.  Cell therapy: cGMP facilities and manufacturing.

Authors:  Raffaella Giancola; Tiziana Bonfini; Antonio Iacone
Journal:  Muscles Ligaments Tendons J       Date:  2012-10-16

Review 3.  Stem cells: roadmap to the clinic.

Authors:  George Q Daley
Journal:  J Clin Invest       Date:  2010-01       Impact factor: 14.808

4.  From embryonic stem cells to iPS - an ethical perspective.

Authors:  J Suaudeau
Journal:  Cell Prolif       Date:  2011-04       Impact factor: 6.831

Review 5.  Tooth-derived stem cells: Update and perspectives.

Authors:  Miki Taketomi Saito; Karina Gonzales Silvério; Márcio Zaffalon Casati; Enilson Antonio Sallum; Francisco Humberto Nociti
Journal:  World J Stem Cells       Date:  2015-03-26       Impact factor: 5.326

Review 6.  A periodic table of cell types.

Authors:  Bo Xia; Itai Yanai
Journal:  Development       Date:  2019-06-27       Impact factor: 6.868

Review 7.  Effects of nicotine on the translation of stem cell therapy.

Authors:  Alex Hp Chan; Ngan F Huang
Journal:  Regen Med       Date:  2020-07-03       Impact factor: 3.806

Review 8.  Adipose Tissue-Derived Stem Cells in Regenerative Medicine.

Authors:  Laura Frese; Petra E Dijkman; Simon P Hoerstrup
Journal:  Transfus Med Hemother       Date:  2016-07-26       Impact factor: 3.747

9.  Enhanced survival and neurite network formation of human umbilical cord blood neuronal progenitors in three-dimensional collagen constructs.

Authors:  Marian M Bercu; Hadar Arien-Zakay; Dana Stoler; Shimon Lecht; Peter I Lelkes; Simcha Samuel; Reuven Or; Arnon Nagler; Philip Lazarovici; Uriel Elchalal
Journal:  J Mol Neurosci       Date:  2012-12-12       Impact factor: 3.444

10.  The evolution of policy issues in stem cell research: an international survey.

Authors:  Timothy Caulfield; Christen Rachul; Amy Zarzeczny
Journal:  Stem Cell Rev Rep       Date:  2012-12       Impact factor: 5.739

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