BACKGROUND: Eighty percent of people with Guillain-Barré Syndrome (GBS) are said to achieve 'good' outcome. 'Good' outcome has been defined as either of the top two scores (0 = Healthy, 1 = minor symptoms or signs, able to run) on a 7-point ordinal scale called the F-score. This assessment of 'good' outcome appears to be an arbitrary benchmark. This study is the first assessment of the differences in outcome between post-acute GBS sufferers reporting these scores. It attempts to compare the physical and emotional differences between respondents reporting '0' and '1' on the F-Score. METHODS: A postal survey was administered to respondents through the UK Guillain-Barré Syndrome Support Group's national database and included items relating to general patient data, general mobility, F-Score, Hospital Anxiety and Depression Scale, SF 36 and Fatigue Severity Scale. RESULTS: One thousand five hundred and thirty-five members were surveyed, and of 884/1535 (58%) questionnaires were returned. Results indicate significant differences between those scoring '0' on the F-Score and those scoring '1' in the post-acute phase in terms of anxiety, depression, physical functioning, fatigue and wheelchair use on discharge. CONCLUSIONS: Significantly poorer outcomes for those scoring '1' on the F-Score suggest that only those scoring '0' should constitute a 'good' outcome in GBS.
BACKGROUND: Eighty percent of people with Guillain-Barré Syndrome (GBS) are said to achieve 'good' outcome. 'Good' outcome has been defined as either of the top two scores (0 = Healthy, 1 = minor symptoms or signs, able to run) on a 7-point ordinal scale called the F-score. This assessment of 'good' outcome appears to be an arbitrary benchmark. This study is the first assessment of the differences in outcome between post-acute GBS sufferers reporting these scores. It attempts to compare the physical and emotional differences between respondents reporting '0' and '1' on the F-Score. METHODS: A postal survey was administered to respondents through the UK Guillain-Barré Syndrome Support Group's national database and included items relating to general patient data, general mobility, F-Score, Hospital Anxiety and Depression Scale, SF 36 and Fatigue Severity Scale. RESULTS: One thousand five hundred and thirty-five members were surveyed, and of 884/1535 (58%) questionnaires were returned. Results indicate significant differences between those scoring '0' on the F-Score and those scoring '1' in the post-acute phase in terms of anxiety, depression, physical functioning, fatigue and wheelchair use on discharge. CONCLUSIONS: Significantly poorer outcomes for those scoring '1' on the F-Score suggest that only those scoring '0' should constitute a 'good' outcome in GBS.
Authors: L Schirmer; V Worthington; U Solloch; V Loleit; V Grummel; N Lakdawala; D Grant; R Wassmuth; A H Schmidt; F Gebhardt; T F M Andlauer; J Sauter; A Berthele; M P Lunn; Bernhard Hemmer Journal: J Neurol Date: 2016-08-02 Impact factor: 4.849
Authors: J Witsch; N Galldiks; A Bender; R Kollmar; J Bösel; C Hobohm; A Günther; I Schirotzek; K Fuchs; E Jüttler Journal: J Neurol Date: 2013-01-09 Impact factor: 4.849