Literature DB >> 20049572

Postoperative analgesia in TKA: ropivacaine continuous intraarticular infusion.

Primitivo Gómez-Cardero1, E Carlos Rodríguez-Merchán.   

Abstract

BACKGROUND: Postoperative pain control is a challenge in patients undergoing TKA due to side effects and technical limitations of current analgesic approaches. Local anesthetic infiltration through continuous infusion pumps has been shown to reduce postoperative pain in previous studies. QUESTIONS/PURPOSES: We assessed the effectiveness of intraarticular ropivacaine infusions in reducing pain and postoperative opioid use after TKA and determined whether such infusions accelerate functional recovery of the patient and reduce length of hospital stay.
METHODS: In a randomized, prospective, double-blind study, two groups were assigned: Group A (n = 25) underwent continuous intraarticular infusion with 300 mL ropivacaine 0.2% at a speed of 5 mL/hour through an elastomeric infusion pump and Group B (n = 25) had an elastomeric pump insertion with 300 mL saline solution at an infusion speed of 5 mL/hour. All patients had the same prosthesis model implanted. Parameters analyzed over the first 3 days, at discharge, and 1 month later included postoperative pain, joint function, opioid use, and length of hospital stay.
RESULTS: All patients in Group A showed a decrease in pain intensity measured by a visual analog scale and opioid use in the first 3 days. Mean length of hospital stay was also reduced in Group A (5.72 days) compared to Group B (7.32 days). There were no device-related complications.
CONCLUSIONS: Use of an infusion pump is effective in treating pain after TKA, reducing postoperative pain and opioid use. It also improves immediate functionality and patient comfort, reducing the mean length of hospital stay, without increasing the risk of complications. LEVEL OF EVIDENCE: Level I, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20049572      PMCID: PMC2853675          DOI: 10.1007/s11999-009-1202-2

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  22 in total

1.  Continuous intra-articular infusion of bupivacaine for postoperative pain following total knee arthroplasty.

Authors:  Jeffrey Nechleba; Vincent Rogers; Gary Cortina; Timothy Cooney
Journal:  J Knee Surg       Date:  2005-07       Impact factor: 2.757

2.  Accelerated rehabilitation after total knee replacement.

Authors:  David Isaac; Tunde Falode; Phong Liu; Helen I'Anson; Katherine Dillow; Paul Gill
Journal:  Knee       Date:  2005-10       Impact factor: 2.199

Review 3.  Local anesthetics as antimicrobial agents: a review.

Authors:  Svena M Johnson; Barbara E Saint John; Alan P Dine
Journal:  Surg Infect (Larchmt)       Date:  2008-04       Impact factor: 2.150

4.  A multimodal analgesia protocol for total knee arthroplasty. A randomized, controlled study.

Authors:  Pascal-André Vendittoli; Patrice Makinen; Pierre Drolet; Martin Lavigne; Michel Fallaha; Marie-Claude Guertin; France Varin
Journal:  J Bone Joint Surg Am       Date:  2006-02       Impact factor: 5.284

5.  Increased flexion and reduced hospital stay with continuous intraarticular morphine and ropivacaine after primary total knee replacement: open intervention study of efficacy and safety in 154 patients.

Authors:  Sten Rasmussen; Morten U Kramhøft; Kim P Sperling; Jens H L Pedersen
Journal:  Acta Orthop Scand       Date:  2004-10

6.  Efficacy of periarticular multimodal drug injection in total knee arthroplasty. A randomized trial.

Authors:  Constant A Busch; Benjamin J Shore; Rakesh Bhandari; Su Ganapathy; Steven J MacDonald; Robert B Bourne; Cecil H Rorabeck; Richard W McCalden
Journal:  J Bone Joint Surg Am       Date:  2006-05       Impact factor: 5.284

7.  Serum and wound drain ropivacaine concentrations after wound infiltration in joint arthroplasty.

Authors:  Bruce W Stringer; Aloke K Singhania; Joe E Sudhakar; Rodney B Brink
Journal:  J Arthroplasty       Date:  2007-07-25       Impact factor: 4.757

8.  Multimodal pain management after total hip and knee arthroplasty at the Ranawat Orthopaedic Center.

Authors:  Aditya V Maheshwari; Yossef C Blum; Laghvendu Shekhar; Amar S Ranawat; Chitranjan S Ranawat
Journal:  Clin Orthop Relat Res       Date:  2009-02-13       Impact factor: 4.176

9.  Comparison of peri- and intraarticular analgesia with femoral nerve block after total knee arthroplasty: a randomized clinical trial.

Authors:  Karen Toftdahl; Lone Nikolajsen; Viggo Haraldsted; Frank Madsen; Else K Tønnesen; Kjeld Søballe
Journal:  Acta Orthop       Date:  2007-04       Impact factor: 3.717

Review 10.  [Frequency, intensity, development and repercussions of postoperative pain as a function of the type of surgery].

Authors:  M Beaussier
Journal:  Ann Fr Anesth Reanim       Date:  1998
View more
  25 in total

1.  [Postoperative analgesia after total knee arthroplasty: Continuous intra-articular catheter vs. continuous femoral nerve block].

Authors:  K P Kutzner; C Paulini; M Hechtner; P Rehbein; J Pfeil
Journal:  Orthopade       Date:  2015-07       Impact factor: 1.087

2.  Local infiltration analgesia adds no clinical benefit in pain control to peripheral nerve blocks after total knee arthroplasty.

Authors:  Pedro Hinarejos; Bruno Capurro; Xavier Santiveri; Pere Ortiz; Joan Leal; Xavier Pelfort; Raul Torres-Claramunt; Juan Sánchez-Soler; Joan C Monllau
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-06-14       Impact factor: 4.342

3.  Local infiltration analgesia with additional intraarticular catheter provide better pain relief compared to single-shot local infiltration analgesia in TKA.

Authors:  Malin Meier; Sarah Sommer; Jochen Huth; Christian Benignus; Emmanuel Thienpont; Johannes Beckmann
Journal:  Arch Orthop Trauma Surg       Date:  2020-09-19       Impact factor: 3.067

4.  The 2012 Chitranjan Ranawat award: intraarticular analgesia after TKA reduces pain: a randomized, double-blinded, placebo-controlled, prospective study.

Authors:  Nitin Goyal; James McKenzie; Peter F Sharkey; Javad Parvizi; William J Hozack; Matthew S Austin
Journal:  Clin Orthop Relat Res       Date:  2013-01       Impact factor: 4.176

5.  Intra-articular Analgesia and Discharge to Home Enhance Recovery Following Total Knee Replacement.

Authors:  Shivi Duggal; Susan Flics; Charles N Cornell
Journal:  HSS J       Date:  2014-11-12

6.  Local infusion analgesia using intra-articular double lumen catheter after total knee arthroplasty: a double blinded randomized control study.

Authors:  Masahiko Ikeuchi; Yuko Kamimoto; Masashi Izumi; Natsuki Sugimura; Mizue Takemura; Kayo Fukunaga; Masataka Yokoyama; Toshikazu Tani
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2012-04-11       Impact factor: 4.342

Review 7.  Preventive analgesia by local anesthetics: the reduction of postoperative pain by peripheral nerve blocks and intravenous drugs.

Authors:  Antje Barreveld; Jürgen Witte; Harkirat Chahal; Marcel E Durieux; Gary Strichartz
Journal:  Anesth Analg       Date:  2013-02-13       Impact factor: 5.108

8.  Is pain after TKA better with periarticular injection or intrathecal morphine?

Authors:  Nattapol Tammachote; Supakit Kanitnate; Sudsayam Manuwong; Thanasak Yakumpor; Phonthakorn Panichkul
Journal:  Clin Orthop Relat Res       Date:  2013-02-09       Impact factor: 4.176

9.  No advantage of adrenaline in the local infiltration analgesia mixture during total knee arthroplasty.

Authors:  Martijn G M Schotanus; Yoeri F L Bemelmans; P Hugo M van der Kuy; Jacqueline Jansen; Nanne P Kort
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-07-26       Impact factor: 4.342

10.  Intraarticular analgesia versus epidural plus femoral nerve block after TKA: a randomized, double-blind trial.

Authors:  Keith R Reinhardt; Shivi Duggal; Ben-Paul Umunna; Gregory A Reinhardt; Denis Nam; Michael Alexiades; Charles N Cornell
Journal:  Clin Orthop Relat Res       Date:  2014-05       Impact factor: 4.176

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.