| Literature DB >> 20046401 |
Se-Hoon Shim1, Yeon-Jeong Lee, Eun-Chan Lee.
Abstract
Escitalopram is one of the most popular selective serotonin reuptake inhibitors (SSRIs) in current use as a first-line treatment for depression. Escitalopram is well-tolerated and rarely associated with serious side effects. Endocrine and reproductive side effects of serotonergic antidepressants are uncommon and galactorrhea is very rarely mentioned among SSRI-related side effects. Serotonin-enhancing antidepressants may result in a rise in prolactin levels through suppression of dopamine neurotransmission. In the present study, we report a case of hyperprolactinemic galactorrhea associated with escitalopram. A 36-year-old woman developed galactorrhea after initiation of escitalopram for depression and was found to have an elevated prolactin level. Escitalopram was discontinued with resolution of the patient's galactorrhea and normalization of her prolactin level.Entities:
Keywords: Depression; Escitalopram; Galactorrhea; Prolactin; Side effect
Year: 2009 PMID: 20046401 PMCID: PMC2796073 DOI: 10.4306/pi.2009.6.3.230
Source DB: PubMed Journal: Psychiatry Investig ISSN: 1738-3684 Impact factor: 2.505