Literature DB >> 20046321

Controversies in the management of bacterial meningitis.

Trenna Sutcliffe1.   

Abstract

Bacterial meningitis is an important infection of childhood with significant morbidity and mortality, and clinicians are faced with controversies over steroid use and fluid restriction in its initial management because the standard of practice is not clear. A 1999 survey of paediatric infectious diseases specialists demonstrated that only 56% of respondents recommended dexamethasone for Haemophilus influenzae type b meningitis and only 34% recommended dexamethasone for Streptococcus pneumoniae meningitis, despite recommendations for dexamethasone in the 1997 Red Book. The present article illustrates a typical case presentation of bacterial meningitis, and discusses dexamethasone use and fluid restriction. The use of intravenous fluid therapy is also reviewed, based on results from the single prospective randomized clinical trial in this area.

Entities:  

Keywords:  Bacterial meningitis; Dexamethasone; Fluid management; Meningitis

Year:  2002        PMID: 20046321      PMCID: PMC2795673          DOI: 10.1093/pch/7.7.449

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN: 1205-7088            Impact factor:   2.253


  20 in total

1.  Effect of hydration status on cerebral blood flow and cerebrospinal fluid lactic acidosis in rabbits with experimental meningitis.

Authors:  J H Tureen; M G Täuber; M A Sande
Journal:  J Clin Invest       Date:  1992-03       Impact factor: 14.808

2.  Lack of adverse effects of dexamethasone therapy in aseptic meningitis.

Authors:  D C Waagner; W A Kennedy; M J Hoyt; G H McCracken
Journal:  Pediatr Infect Dis J       Date:  1990-12       Impact factor: 2.129

3.  Evidence for fluid volume depletion in hyponatraemic patients with bacterial meningitis.

Authors:  M G Bianchetti; H R Thyssen; R Laux-End; U B Schaad
Journal:  Acta Paediatr       Date:  1996-10       Impact factor: 2.299

4.  Dexamethasone as adjunctive therapy in bacterial meningitis. A meta-analysis of randomized clinical trials since 1988.

Authors:  P B McIntyre; C S Berkey; S M King; U B Schaad; T Kilpi; G Y Kanra; C M Perez
Journal:  JAMA       Date:  1997-09-17       Impact factor: 56.272

5.  Dexamethasone therapy for bacterial meningitis. Results of two double-blind, placebo-controlled trials.

Authors:  M H Lebel; B J Freij; G A Syrogiannopoulos; D F Chrane; M J Hoyt; S M Stewart; B D Kennard; K D Olsen; G H McCracken
Journal:  N Engl J Med       Date:  1988-10-13       Impact factor: 91.245

6.  Changes in body water compartments in children with acute meningitis.

Authors:  V Kumar; P Singhi; S Singhi
Journal:  Pediatr Infect Dis J       Date:  1994-04       Impact factor: 2.129

7.  Prevention of hearing loss in experimental pneumococcal meningitis by administration of dexamethasone and ketorolac.

Authors:  J M Rappaport; S M Bhatt; R F Burkard; S N Merchant; J B Nadol
Journal:  J Infect Dis       Date:  1999-01       Impact factor: 5.226

8.  Influence of dexamethasone on efficacy of ceftriaxone and vancomycin therapy in experimental pneumococcal meningitis.

Authors:  C Cabellos; J Martinez-Lacasa; A Martos; F Tubau; A Fernández; P F Viladrich; F Gudiol
Journal:  Antimicrob Agents Chemother       Date:  1995-09       Impact factor: 5.191

9.  Oral glycerol and intravenous dexamethasone in preventing neurologic and audiologic sequelae of childhood bacterial meningitis. The Finnish Study Group.

Authors:  T Kilpi; H Peltola; T Jauhiainen; M J Kallio
Journal:  Pediatr Infect Dis J       Date:  1995-04       Impact factor: 2.129

10.  Effectiveness of adjunctive treatment with steroids in reducing short-term mortality in a high-risk population of children with bacterial meningitis.

Authors:  G Ciana; N Parmar; C Antonio; S Pivetta; G Tamburlini; M Cuttini
Journal:  J Trop Pediatr       Date:  1995-06       Impact factor: 1.165

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