Literature DB >> 200457

Cholesterol synthesis in freshly isolated human leukocytes.

P Tarugi, V Romoli, F Crovetti, S Calandra.   

Abstract

Cholesterol synthesis has been studied in human leukocytes shortly after the isolation from healthy subjects. Not delipidated human serum reduced the cholesterol synthesis when added to the incubation medium. A similar effect was obtained when the leukocytes were incubated in the presence of physiological concentrations of low density lipoproteins.

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Year:  1977        PMID： 200457     DOI： 10.1007/bf01918783

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  18 in total

1.  Leukocyte preparations from human blood: evaluation of their morphologic and metabolic state.

Authors:  H J FALLON; E FREI; J D DAVIDSON; J S TRIER; D BURK
Journal:  J Lab Clin Med       Date:  1962-05

2.  Studies on the fibrinogen, dextran and phytohemagglutinin methods of isolating leukocytes.

Authors:  W A SKOOG; W S BECK
Journal:  Blood       Date:  1956-05       Impact factor: 22.113

3.  Uptake and catabolism of low density lipoprotein by human lymphocytes.

Authors:  D Reichl; A Postiglione; N B Myant
Journal:  Nature       Date:  1976-04-15       Impact factor: 49.962

4.  Receptor-mediated control of cholesterol metabolism.

Authors:  M S Brown; J L Goldstein
Journal:  Science       Date:  1976-01-16       Impact factor: 47.728

5.  Regulation of the activity of the low density lipoprotein receptor in human fibroblasts.

Authors:  M S Brown; J L Goldstein
Journal:  Cell       Date:  1975-11       Impact factor: 41.582

6.  Regulation of cholesterol biosynthesis in rat liver after the administration of N-2-fluorenylacetamide.

Authors:  S Calandra; D Guariento; F Rivasi
Journal:  Lab Invest       Date:  1973-06       Impact factor: 5.662

7.  Cholesterol synthesis by cultured fibroblasts: decreased feedback inhibition in familial hypercholesterolemia.

Authors:  A K Khachadurian; F S Kawahara
Journal:  J Lab Clin Med       Date:  1974-01

8.  Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and the esterification of cholesterol in human long term lymphoid cell lines.

Authors:  H J Kayden; L Hatam; N G Beratis
Journal:  Biochemistry       Date:  1976-02-10       Impact factor: 3.162

9.  Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.

Authors:  M S Brown; S E Dana; J L Goldstein
Journal:  J Biol Chem       Date:  1974-02-10       Impact factor: 5.157

10.  In vitro effects of serum proteins and lipids on lipid synthesis in human skin fibroblasts and leukocytes grown in culture.

Authors:  C D Williams; J Avigan
Journal:  Biochim Biophys Acta       Date:  1972-03-23
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