Literature DB >> 20045196

Absence of weight gain association with the HTR2C -759C/T polymorphism in patients with schizophrenia treated with iloperidone.

Andrew Thompson1, Christian Lavedan, Simona Volpi.   

Abstract

Weight gain is a common side effect of antipsychotics, contributing to poor treatment adherence, and previously linked to the -759C/T polymorphism near the serotonin receptor 2C gene. The effect of this polymorphism was analyzed in schizophrenia patients treated with iloperidone for up to 7 months. No association was detected with the modest weight changes observed in these patients. 2009 Elsevier Ltd. All rights reserved.

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Year:  2009        PMID： 20045196     DOI： 10.1016/j.psychres.2009.03.020

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  9 in total

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Authors:  Marc De Hert; Weiping Yu; Johan Detraux; Kim Sweers; Ruud van Winkel; Christoph U Correll
Journal:  CNS Drugs       Date:  2012-09-01       Impact factor: 5.749

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Authors:  Jian-Ping Zhang; Todd Lencz; Ryan X Zhang; Masahiro Nitta; Lawrence Maayan; Majnu John; Delbert G Robinson; W Wolfgang Fleischhacker; Rene S Kahn; Roel A Ophoff; John M Kane; Anil K Malhotra; Christoph U Correll
Journal:  Schizophr Bull       Date:  2016-05-23       Impact factor: 9.306

Review 7.  Iloperidone in the treatment of schizophrenia: an evidence-based review of its place in therapy.

Authors:  Fernanda S Tonin; Astrid Wiens; Fernando Fernandez-Llimos; Roberto Pontarolo
Journal:  Core Evid       Date:  2016-12-14

8.  Association of the HTR2C-759C/T polymorphism and antipsychotic-induced weight gain: a meta-analysis.

Authors:  Yan Chen; Yewei Wang; Xinyu Fang; Yi Zhang; Lisheng Song; Chen Zhang
Journal:  Gen Psychiatr       Date:  2020-05-14

9.  Association between HTR2C gene variants and suicidal behaviour: a protocol for the systematic review and meta-analysis of genetic studies.

Authors:  González-Castro Thelma Beatriz; Juárez-Rojop Isela; Genis Alma; López-Narváez María Lilia; Tovilla-Zárate Carlos Alfonso
Journal:  BMJ Open       Date:  2014-09-04       Impact factor: 2.692
  9 in total

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