Literature DB >> 20044

Comparative stability of cephalothin and cefazolin in buffer or human serum.

D Pitkin, P Actor, J J Filan, R White, J A Weisbach.   

Abstract

A marked loss in potency was observed when cephalothin was incubated for 5 h in human serum at 37 degrees C. Cefazolin was stable under these conditions.

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Year:  1977        PMID： 20044      PMCID： PMC429898          DOI： 10.1128/AAC.12.2.284

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  2 in total

1.  Comparative stability of cephalosporins in aqueous solution: kinetics and mechanisms of degradation.

Authors:  T Yamana; A Tsuji
Journal:  J Pharm Sci       Date:  1976-11       Impact factor: 3.534

2.  Stability of cephalosporins in horse serum.

Authors:  M A Foglesong
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191
  2 in total

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