UNLABELLED: We evaluated the sensitivity for the anti-HIV antibody detection of the 8 rapid disposable tests (RDTs) EC approved in 2008. METHODS: A panel of 100 native serum samples collected from HIV-1 subtype B or non-B, HIV-1 group O or HIV-2-infected patient and 3 commercial seroconversion panels were tested. 50 sera from HIV-negative patients were included to blind reading and RDT specificity. RESULTS: All native samples HIV-1 subtype B were reactive; an HIV-1 non-B subtype gave false-negative results with 3 of the 8 tests. False-negative results on HIV-1 group O samples were observed with one RDT. All the HIV-2 samples were detected. Seroconversion sample reactivity ranged from 60 to 86.7% according to the tests. CONCLUSION: Despite their lower performances relative to ELISA tests during the HIV seroconversion period, RDT may be of interest in case of chronic infection. Copyright (c) 2009 Elsevier B.V. All rights reserved.
UNLABELLED: We evaluated the sensitivity for the anti-HIV antibody detection of the 8 rapid disposable tests (RDTs) EC approved in 2008. METHODS: A panel of 100 native serum samples collected from HIV-1 subtype B or non-B, HIV-1 group O or HIV-2-infectedpatient and 3 commercial seroconversion panels were tested. 50 sera from HIV-negative patients were included to blind reading and RDT specificity. RESULTS: All native samples HIV-1 subtype B were reactive; an HIV-1 non-B subtype gave false-negative results with 3 of the 8 tests. False-negative results on HIV-1 group O samples were observed with one RDT. All the HIV-2 samples were detected. Seroconversion sample reactivity ranged from 60 to 86.7% according to the tests. CONCLUSION: Despite their lower performances relative to ELISA tests during the HIV seroconversion period, RDT may be of interest in case of chronic infection. Copyright (c) 2009 Elsevier B.V. All rights reserved.
Authors: Judith Harbertson; Braden R Hale; Bonnie R Tran; Anne G Thomas; Michael P Grillo; Marni B Jacobs; Jennifer McAnany; Richard A Shaffer Journal: PLoS One Date: 2017-07-07 Impact factor: 3.240
Authors: Paola Scognamiglio; Giacomina Chiaradia; Marta Giovanetti; Emidio Albertini; Antonella Camposeragna; Massimo Farinella; Daniela Lorenzetti; Massimo Oldrini; Laura Rancilio; Anna Caraglia; Francesco Paolo Maraglino; Giuseppe Ippolito; Enrico Girardi Journal: BMC Public Health Date: 2018-06-18 Impact factor: 3.295