Slow heart-slow brain: consequence of short-term occupational exposure to toluene in a young woman: what is the real mechanism?

Herein we describe a case of acute occupational exposure to toluene in a 27-year-old female patient, presented to the emergency department of our institute. On admission she had electrocardiographic signs of profound sinus bradycardia with sinus arrhythmia and low amplitude slow wave activity recorded on her electroencephalogram (EEG). The mechanisms underlying the cerebral and cardiac effects of toluene are also discussed. Copyright 2010 Wiley Periodicals, Inc.