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Literature DB >> 20043031

Orphan products: an emerging trend in drug approvals.

Timothy Coté, Aditya Kelkar, Kui Xu, M Miles Braun, M Ian Phillips.

Abstract

Mesh：

Year: 2010 PMID： 20043031 DOI： 10.1038/nrd2546-c1

Source DB: PubMed Journal: Nat Rev Drug Discov ISSN： 1474-1776 Impact factor: 84.694

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2 in total

1. Adopting orphan drugs--two dozen years of treating rare diseases.

Authors: Marlene E Haffner
Journal: N Engl J Med Date: 2006-02-02 Impact factor: 91.245

2. Market incentives and pharmaceutical innovation.

Authors: Wesley Yin
Journal: J Health Econ Date: 2008-02-17 Impact factor: 3.883

2 in total

7 in total

Review 1. The productivity crisis in pharmaceutical R&D.

Authors: Fabio Pammolli; Laura Magazzini; Massimo Riccaboni
Journal: Nat Rev Drug Discov Date: 2011-06 Impact factor: 84.694

Review 2. An empirical review of major legislation affecting drug development: past experiences, effects, and unintended consequences.

Authors: Aaron S Kesselheim
Journal: Milbank Q Date: 2011-09 Impact factor: 4.911

3. Introduction to a supplement on innovative approaches to studying health outcomes in rare diseases.

Authors: Aaron S Kesselheim; Joshua J Gagne
Journal: J Gen Intern Med Date: 2014-08 Impact factor: 5.128

Review 4. Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease.

Authors: Elizabeth A Ottinger; Mark L Kao; Nuria Carrillo-Carrasco; Nicole Yanjanin; Roopa Kanakatti Shankar; Marjo Janssen; Marcus Brewster; Ilona Scott; Xin Xu; Jim Cradock; Pramod Terse; Seameen J Dehdashti; Juan Marugan; Wei Zheng; Lili Portilla; Alan Hubbs; William J Pavan; John Heiss; Charles H Vite; Steven U Walkley; Daniel S Ory; Steven A Silber; Forbes D Porter; Christopher P Austin; John C McKew
Journal: Curr Top Med Chem Date: 2014 Impact factor: 3.295