Literature DB >> 20042511

Naturally occurring human monoclonal antibodies neutralize both 1918 and 2009 pandemic influenza A (H1N1) viruses.

Jens C Krause1, Terrence M Tumpey, Chelsey J Huffman, Patricia A McGraw, Melissa B Pearce, Tshidi Tsibane, Rong Hai, Christopher F Basler, James E Crowe.   

Abstract

The 2009 pandemic influenza A (H1N1) virus exhibits hemagglutinin protein sequence homology with the 1918 pandemic influenza virus. We found that human monoclonal antibodies recognized the Sa antigenic site on the head domains of both 1918 and 2009 hemagglutinins, a site that is hypervariable due to immune selection. These antibodies exhibited high potency against the 2009 virus in vitro, and one exerted a marked therapeutic effect in vivo.

Entities:  

Mesh：

Substances：

Year:  2009        PMID： 20042511      PMCID： PMC2826039          DOI： 10.1128/JVI.02184-09

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

1.  Characterization of the reconstructed 1918 Spanish influenza pandemic virus.

Authors:  Terrence M Tumpey; Christopher F Basler; Patricia V Aguilar; Hui Zeng; Alicia Solórzano; David E Swayne; Nancy J Cox; Jacqueline M Katz; Jeffery K Taubenberger; Peter Palese; Adolfo García-Sastre
Journal:  Science       Date:  2005-10-07       Impact factor: 47.728

2.  Antigenic variation in three distinct determinants of an influenza type A haemagglutinin molecule.

Authors:  J W Yewdell; R G Webster; W U Gerhard
Journal:  Nature       Date:  1979-05-17       Impact factor: 49.962

3.  The antigenic structure of the influenza virus A/PR/8/34 hemagglutinin (H1 subtype).

Authors:  A J Caton; G G Brownlee; J W Yewdell; W Gerhard
Journal:  Cell       Date:  1982-12       Impact factor: 41.582

4.  Evaluation of hemagglutinin subtype 1 swine influenza viruses from the United States.

Authors:  Amy L Vincent; Kelly M Lager; Wenjun Ma; Porntippa Lekcharoensuk; Marie R Gramer; Christina Loiacono; Juergen A Richt
Journal:  Vet Microbiol       Date:  2006-08-01       Impact factor: 3.293

5.  Antigenic conservation of H1N1 swine influenza viruses.

Authors:  M G Sheerar; B C Easterday; V S Hinshaw
Journal:  J Gen Virol       Date:  1989-12       Impact factor: 3.891

6.  Outbreak of swine-origin influenza A (H1N1) virus infection - Mexico, March-April 2009.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2009-05-08       Impact factor: 17.586

7.  Antigenic structure of influenza virus haemagglutinin defined by hybridoma antibodies.

Authors:  W Gerhard; J Yewdell; M E Frankel; R Webster
Journal:  Nature       Date:  1981-04-23       Impact factor: 49.962

8.  Transmission and pathogenesis of swine-origin 2009 A(H1N1) influenza viruses in ferrets and mice.

Authors:  Taronna R Maines; Akila Jayaraman; Jessica A Belser; Debra A Wadford; Claudia Pappas; Hui Zeng; Kortney M Gustin; Melissa B Pearce; Karthik Viswanathan; Zachary H Shriver; Rahul Raman; Nancy J Cox; Ram Sasisekharan; Jacqueline M Katz; Terrence M Tumpey
Journal:  Science       Date:  2009-07-02       Impact factor: 47.728

9.  Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors.

Authors:  Xiaocong Yu; Tshidi Tsibane; Patricia A McGraw; Frances S House; Christopher J Keefer; Mark D Hicar; Terrence M Tumpey; Claudia Pappas; Lucy A Perrone; Osvaldo Martinez; James Stevens; Ian A Wilson; Patricia V Aguilar; Eric L Altschuler; Christopher F Basler; James E Crowe
Journal:  Nature       Date:  2008-08-17       Impact factor: 49.962

10.  Antibody recognition of a highly conserved influenza virus epitope.

Authors:  Damian C Ekiert; Gira Bhabha; Marc-André Elsliger; Robert H E Friesen; Mandy Jongeneelen; Mark Throsby; Jaap Goudsmit; Ian A Wilson
Journal:  Science       Date:  2009-02-26       Impact factor: 47.728
View more
  55 in total

1.  Amino acid sequence analysis and identification of mutations under positive selection in hemagglutinin of 2009 influenza A (H1N1) isolates.

Authors:  Xiaofan Ding; Lifang Jiang; Changwen Ke; Zhan Yang; Chunliang Lei; Kaiyuan Cao; Jun Xu; Lin Xu; Xingfen Yang; Yonghui Zhang; Ping Huang; Weijun Huang; Xun Zhu; Zhenjian He; Liping Liu; Jun Li; Jie Yuan; Jueheng Wu; Xiaoping Tang; Mengfeng Li
Journal:  Virus Genes       Date:  2010-08-31       Impact factor: 2.332

2.  Structural basis of preexisting immunity to the 2009 H1N1 pandemic influenza virus.

Authors:  Rui Xu; Damian C Ekiert; Jens C Krause; Rong Hai; James E Crowe; Ian A Wilson
Journal:  Science       Date:  2010-03-25       Impact factor: 47.728

3.  Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.

Authors:  Scott A Smith; Laurie A Silva; Julie M Fox; Andrew I Flyak; Nurgun Kose; Gopal Sapparapu; Solomiia Khomandiak; Solomiia Khomadiak; Alison W Ashbrook; Kristen M Kahle; Rachel H Fong; Sherri Swayne; Benjamin J Doranz; Charles E McGee; Mark T Heise; Pankaj Pal; James D Brien; S Kyle Austin; Michael S Diamond; Terence S Dermody; James E Crowe
Journal:  Cell Host Microbe       Date:  2015-07-08       Impact factor: 21.023

4.  Contact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strains.

Authors:  Paul S Wikramaratna; Oliver G Pybus; Sunetra Gupta
Journal:  Proc Natl Acad Sci U S A       Date:  2014-06-23       Impact factor: 11.205

5.  Epitope-specific human influenza antibody repertoires diversify by B cell intraclonal sequence divergence and interclonal convergence.

Authors:  Jens C Krause; Tshidi Tsibane; Terrence M Tumpey; Chelsey J Huffman; Bryan S Briney; Scott A Smith; Christopher F Basler; James E Crowe
Journal:  J Immunol       Date:  2011-08-31       Impact factor: 5.422

Review 6.  The influenza pandemic of 2009: lessons and implications.

Authors:  Paul Shapshak; Francesco Chiappelli; Charurut Somboonwit; John Sinnott
Journal:  Mol Diagn Ther       Date:  2011-04-01       Impact factor: 4.074

7.  Vaccinate for the next H2N2 pandemic now.

Authors:  Gary J Nabel; Chih-Jen Wei; Julie E Ledgerwood
Journal:  Nature       Date:  2011-03-10       Impact factor: 49.962

Review 8.  Principles of Broad and Potent Antiviral Human Antibodies: Insights for Vaccine Design.

Authors:  James E Crowe
Journal:  Cell Host Microbe       Date:  2017-08-09       Impact factor: 21.023

9.  H7N9 influenza virus neutralizing antibodies that possess few somatic mutations.

Authors:  Natalie J Thornburg; Heng Zhang; Sandhya Bangaru; Gopal Sapparapu; Nurgun Kose; Rebecca M Lampley; Robin G Bombardi; Yingchun Yu; Stephen Graham; Andre Branchizio; Sandra M Yoder; Michael T Rock; C Buddy Creech; Kathryn M Edwards; David Lee; Sheng Li; Ian A Wilson; Adolfo García-Sastre; Randy A Albrecht; James E Crowe
Journal:  J Clin Invest       Date:  2016-03-07       Impact factor: 14.808

10.  Pandemic 2009 H1N1 vaccine protects against 1918 Spanish influenza virus.

Authors:  Rafael A Medina; Balaji Manicassamy; Silke Stertz; Christopher W Seibert; Rong Hai; Robert B Belshe; Sharon E Frey; Christopher F Basler; Peter Palese; Adolfo García-Sastre
Journal:  Nat Commun       Date:  2010-06-15       Impact factor: 14.919
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.