Y Xu1, Y Jing, S Ma, F Ma, Y Wang, W Ma, Q Li. 1. Department of Pathology, Xijing Hospital, Fourth Military Medical University, Xi'an, PR China.
Abstract
OBJECTIVE: Angioleiomyoma (vascular leiomyomas, angiomyoma) is a rare, benign soft tissue tumor which consists of a mixture of well-differentiated smooth muscle cells and thick-walled vessels. Here we report a case of angioleiomyoma in the sellar region, which is the first case report of angioleiomyoma at this anatomical location. CLINICAL PRESENTATION: A 53-year-old man was admitted with a medical history of three months episodic headache and one month visual deterioration, both of which progressed gradually. The neurological examination showed nothing remarkable except a slightly decreased adrenocorticotrophic hormone (ACTH) level. Preoperative magnetic resonance imaging revealed a pituitary apoplexy. Gross total resection of the tumor was then performed. PATHOLOGICAL FINDINGS: Histological and immunohistochemical studies showed a typical microscopic appearance of an angioleiomyoma present in a rather uncommon place. The pertinent literature regarding the features of this tumor was reviewed and discussed. CONCLUSIONS: Intracranial angioleiomyoma is a benign soft tissue tumor with excellent prognosis. Early diagnosis of this tumor is difficult.
OBJECTIVE:Angioleiomyoma (vascular leiomyomas, angiomyoma) is a rare, benign soft tissue tumor which consists of a mixture of well-differentiated smooth muscle cells and thick-walled vessels. Here we report a case of angioleiomyoma in the sellar region, which is the first case report of angioleiomyoma at this anatomical location. CLINICAL PRESENTATION: A 53-year-old man was admitted with a medical history of three months episodic headache and one month visual deterioration, both of which progressed gradually. The neurological examination showed nothing remarkable except a slightly decreased adrenocorticotrophic hormone (ACTH) level. Preoperative magnetic resonance imaging revealed a pituitary apoplexy. Gross total resection of the tumor was then performed. PATHOLOGICAL FINDINGS: Histological and immunohistochemical studies showed a typical microscopic appearance of an angioleiomyoma present in a rather uncommon place. The pertinent literature regarding the features of this tumor was reviewed and discussed. CONCLUSIONS:Intracranial angioleiomyoma is a benign soft tissue tumor with excellent prognosis. Early diagnosis of this tumor is difficult.