Literature DB >> 20039643

Cytotoxic halogenated metabolites from the Brazilian red alga Laurencia catarinensis.

Cintia Lhullier1, Miriam Falkenberg, Efstathia Ioannou, Antonio Quesada, Panagiota Papazafiri, Paulo Antunes Horta, Eloir Paulo Schenkel, Constantinos Vagias, Vassilios Roussis.   

Abstract

Seven new (1-7) and seven previously reported (8-14) halogenated metabolites were isolated from the organic extract of the Brazilian red alga Laurencia catarinensis. The structure elucidation and the assignment of the relative configurations of the new natural products were based on detailed NMR and MS spectroscopic analyses, whereas the structure of metabolite 6 was confirmed by single-crystal X-ray diffraction analysis. The absolute configuration of metabolite 1 was determined using the modified Mosher's method. The in vitro cytotoxicity of compounds 1-14 was evaluated against HT29, MCF7, and A431 cell lines.

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Year:  2010        PMID： 20039643     DOI： 10.1021/np900627r

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  Thyrsiferol Inhibits Mitochondrial Respiration and HIF-1 Activation.

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2.  Red algal bromophenols as glucose 6-phosphate dehydrogenase inhibitors.

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Journal:  Mar Drugs       Date:  2013-10-22       Impact factor: 5.118

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Journal:  Mar Drugs       Date:  2015-02-10       Impact factor: 5.118

Review 4.  Chemical Diversity and Biological Properties of Secondary Metabolites from Sea Hares of Aplysia Genus.

Authors:  Renato B Pereira; Paula B Andrade; Patrícia Valentão
Journal:  Mar Drugs       Date:  2016-02-19       Impact factor: 5.118

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Journal:  Molecules       Date:  2017-05-11       Impact factor: 4.411

6.  Fungal strains as catalysts for the biotransformation of halolactones by hydrolytic dehalogenation with the dimethylcyclohexane system.

Authors:  Małgorzata Grabarczyk
Journal:  Molecules       Date:  2012-08-14       Impact factor: 4.411

7.  Thuwalallenes A-E and Thuwalenynes A-C: New C15 Acetogenins with Anti-Inflammatory Activity from a Saudi Arabian Red Sea Laurencia sp.

Authors:  Aikaterini Koutsaviti; Maria G Daskalaki; Susana Agusti; Sotirios C Kampranis; Christos Tsatsanis; Carlos M Duarte; Vassilios Roussis; Efstathia Ioannou
Journal:  Mar Drugs       Date:  2019-11-15       Impact factor: 5.118

8.  Transcriptomic analysis of the red seaweed Laurencia dendroidea (Florideophyceae, Rhodophyta) and its microbiome.

Authors:  Louisi Souza de Oliveira; Gustavo Bueno Gregoracci; Genivaldo Gueiros Zacarias Silva; Leonardo Tavares Salgado; Gilberto Amado Filho; Marcio Alves-Ferreira; Renato Crespo Pereira; Fabiano L Thompson
Journal:  BMC Genomics       Date:  2012-09-17       Impact factor: 3.969

9.  Molecular Mechanisms for Microbe Recognition and Defense by the Red Seaweed Laurencia dendroidea.

Authors:  Louisi Souza de Oliveira; Diogo Antonio Tschoeke; Ana Carolina Rubem Magalhães Lopes; Daniela Bueno Sudatti; Pedro Milet Meirelles; Cristiane C Thompson; Renato Crespo Pereira; Fabiano L Thompson
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  9 in total

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