| Literature DB >> 20037614 |
Tobias Ragoczy, Mark Groudine.
Abstract
A new study provides compelling evidence that transcriptional regulation and three-dimensional genomic architecture are linked. The alpha- and beta-globin loci associate with hundreds of active genes across the genome at transcription factories in erythroid cells, and specialized Klf1-containing transcription factories mediate the association of Klf1-regulated genes.Entities:
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Year: 2010 PMID: 20037614 DOI: 10.1038/ng0110-16
Source DB: PubMed Journal: Nat Genet ISSN: 1061-4036 Impact factor: 38.330