Literature DB >> 20037220

Age-related comparisons of people with multiple sclerosis: demographic, disease, and treatment characteristics.

Robert J Buchanan1, Bonnie J Chakravorty, Tuula Tyry, William Hatcher, Timothy Vollmer.   

Abstract

OBJECTIVE: To determine if the demographic characteristics and health care needs of younger people with MS differ from older people with MS. PARTICIPANTS: The study analyzed enrollment data from the NARCOMS Registry to compare 1,987 younger adults with MS (30 years and younger) to 29,245 other adults with MS (over 30 years).
METHODS: Analyses of the NARCOMS data focused on descriptive characteristics of these adults with MS, using a t-test to identify any statistically significant age-related differences in means and a chi-squared test to identify any statistically significant age-related differences in proportions.
RESULTS: A significantly larger proportion of younger adults with MS were female and African American compared to other adults with MS. We found significant age-related differences in the expression of physical disability domains but few significant age-related differences in symptoms of depression. We also observed significant age-related differences in the utilization of health providers, with larger proportions of other adults with MS treated by internists, urologists, rehabilitation specialists, and physical and occupational therapists.
CONCLUSIONS: The comprehensive care of younger adults with MS should include monitoring for mental health conditions and the availability of mental health services.

Entities:  

Mesh:

Year:  2009        PMID: 20037220     DOI: 10.3233/NRE-2009-0525

Source DB:  PubMed          Journal:  NeuroRehabilitation        ISSN: 1053-8135            Impact factor:   2.138


  9 in total

1.  How Multiple Sclerosis Symptoms Vary by Age, Sex, and Race/Ethnicity.

Authors:  Ilya Kister; Tamar Bacon; Gary R Cutter
Journal:  Neurol Clin Pract       Date:  2021-08

2.  Aging with multiple sclerosis: A longitudinal study of physical function, mental health, and memory in two cohorts of US women.

Authors:  Marianna Cortese; Kjetil Bjornevik; Tanuja Chitnis; Alberto Ascherio; Kassandra L Munger
Journal:  Mult Scler       Date:  2021-04-16       Impact factor: 6.312

3.  Evaluation of an online platform for multiple sclerosis research: patient description, validation of severity scale, and exploration of BMI effects on disease course.

Authors:  Riley Bove; Elizabeth Secor; Brian C Healy; Alexander Musallam; Timothy Vaughan; Bonnie I Glanz; Emily Greeke; Howard L Weiner; Tanuja Chitnis; Paul Wicks; Philip L De Jager
Journal:  PLoS One       Date:  2013-03-20       Impact factor: 3.240

4.  Budget impact analysis of botulinum toxin A therapy for upper limb spasticity in the United Kingdom.

Authors:  Seye Abogunrin; Linda Hortobagyi; Edit Remak; Jerome Dinet; Sylvie Gabriel; Abdel Magid O Bakheit
Journal:  Clinicoecon Outcomes Res       Date:  2015-04-01

Review 5.  Interplay Between Age and Neuroinflammation in Multiple Sclerosis: Effects on Motor and Cognitive Functions.

Authors:  Alessandra Musella; Antonietta Gentile; Francesca Romana Rizzo; Francesca De Vito; Diego Fresegna; Silvia Bullitta; Valentina Vanni; Livia Guadalupi; Mario Stampanoni Bassi; Fabio Buttari; Diego Centonze; Georgia Mandolesi
Journal:  Front Aging Neurosci       Date:  2018-08-08       Impact factor: 5.750

Review 6.  miRNA-Dependent CD4+ T Cell Differentiation in the Pathogenesis of Multiple Sclerosis.

Authors:  Justyna Basak; Ireneusz Majsterek
Journal:  Mult Scler Int       Date:  2021-01-08

7.  Intense inflammation and nerve damage in early multiple sclerosis subsides at older age: a reflection by cerebrospinal fluid biomarkers.

Authors:  Mohsen Khademi; Ann M Dring; Jonathan D Gilthorpe; Anna Wuolikainen; Faiez Al Nimer; Robert A Harris; Magnus Andersson; Lou Brundin; Fredrik Piehl; Tomas Olsson; Anders Svenningsson
Journal:  PLoS One       Date:  2013-05-07       Impact factor: 3.240

8.  The Canadian survey of health, lifestyle and ageing with multiple sclerosis: methodology and initial results.

Authors:  Michelle Ploughman; Serge Beaulieu; Chelsea Harris; Stephen Hogan; Olivia J Manning; Penelope W Alderdice; John D Fisk; A Dessa Sadovnick; Paul O'Connor; Sarah A Morrow; Luanne M Metz; Penelope Smyth; Nancy Mayo; Ruth Ann Marrie; Katherine B Knox; Mark Stefanelli; Marshall Godwin
Journal:  BMJ Open       Date:  2014-07-10       Impact factor: 2.692

9.  EVASEP: A Noninterventional Study Describing the Perception of Neurologists, Patients, and Caregivers on Caregivers' Role in the Support of Patients Suffering from Multiple Sclerosis Treated with Subcutaneous Interferon Beta 1a.

Authors:  Cécile Donzé; Bruno Lenne; Anne-Sophie Jean Deleglise; Christian Kempf; Yasmine Bellili; Patrick Hautecoeur
Journal:  Mult Scler Int       Date:  2016-08-01
  9 in total

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