Literature DB >> 20036474

Percutaneous chemical myotomy using botulium neurtoxin A under local anaesthesia in the treatment of cricopharyngeal dysphagia following laryngectomy.

R S Natt1, M S McCormick, J M Clayton, C Ryall.   

Abstract

OBJECTIVE: The purpose of this study was to evaluate the outcome of the use of percutaneous injection of botulinum neurotoxin A under local anaesthesia in the management of cricophayngeus dysphagia in post-laryngectomy patients.
METHODS: Fifteen post-laryngectomy patients (6 males, 9 females, age range 48-72 years) with surgery performed not less than five years with post-operative radiotherapy were recruited. Under video-fluoroscopic control and the attachment of a metal safety pin to the neck as a topographical marker for the cricopharyngeus muscle, botulinum neurotoxin was injected after local anaesthesia infiltration. Patients were followed up for a 4 months period with repeated video-fluoroscopy and telephone self-assessment and weight change.
RESULTS: Eighty seven percent of patients noticed some improvement in their dysphagia. One patient reported an adverse reaction of pain at the site of injection.
CONCLUSION: Percutaneous local injection of botulinum neurotoxin A is a simple, safe and cost-effective means of improving cricopharyngeal dysphagia in post-laryngectomy patients when general anaesthesia is contra-indicated. Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

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Year:  2009        PMID: 20036474     DOI: 10.1016/j.anl.2009.11.008

Source DB:  PubMed          Journal:  Auris Nasus Larynx        ISSN: 0385-8146            Impact factor:   1.863


  3 in total

1.  European white paper: oropharyngeal dysphagia in head and neck cancer.

Authors:  Laura W J Baijens; Margaret Walshe; Leena-Maija Aaltonen; Christoph Arens; Reinie Cordier; Patrick Cras; Lise Crevier-Buchman; Chris Curtis; Wojciech Golusinski; Roganie Govender; Jesper Grau Eriksen; Kevin Hansen; Kate Heathcote; Markus M Hess; Sefik Hosal; Jens Peter Klussmann; C René Leemans; Denise MacCarthy; Beatrice Manduchi; Jean-Paul Marie; Reza Nouraei; Claire Parkes; Christina Pflug; Walmari Pilz; Julie Regan; Nathalie Rommel; Antonio Schindler; Annemie M W J Schols; Renee Speyer; Giovanni Succo; Irene Wessel; Anna C H Willemsen; Taner Yilmaz; Pere Clavé
Journal:  Eur Arch Otorhinolaryngol       Date:  2020-12-19       Impact factor: 2.503

Review 2.  Airway protective mechanisms.

Authors:  Teresa Pitts
Journal:  Lung       Date:  2013-12-03       Impact factor: 2.584

3.  Diagnosis and treatment of oropharyngeal dysphagia after total laryngectomy with or without pharyngoesophageal reconstruction: Systematic review.

Authors:  Lisanne T Terlingen; Walmari Pilz; Myrthe Kuijer; Bernd Kremer; Laura W Baijens
Journal:  Head Neck       Date:  2018-11-26       Impact factor: 3.147

  3 in total

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